2. PROTAC
  3. PROTAC Linkers
  4. Methylamino-PEG4-Boc

Methylamino-PEG4-Boc  (Synonyms: Methylamino-PEG4-t-butyl ester)

Cat. No.: HY-140156
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Methylamino-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Methylamino-PEG4-Boc Chemical Structure

Methylamino-PEG4-Boc Chemical Structure

CAS No. : 1621616-14-5

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Methylamino-PEG4-Boc Related Antibodies

Top Publications Citing Use of Products

View All PROTAC Linkers Isoform Specific Products:

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PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

  • Biological Activity

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Description

Methylamino-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

Alkyl/ether

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Methylamino-PEG4-Boc Related Antibodies
Molecular Weight

335.44

Formula

C16H33NO6
CAS No.
Appearance

Liquid (Density: 1.015±0.06 g/cm3)

Color

Colorless to light yellow

SMILES

CNCCOCCOCCOCCOCCC(OC(C)(C)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Methylamino-PEG4-Boc Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methylamino-PEG4-Boc1621616-14-5Methylamino-PEG4-t-butyl esterPROTAC LinkersInhibitorinhibitorinhibit

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