1. Natural Products
  2. Disease Research Fields Plants Flavonoids Phenols
  3. Liliaceae Inflammation/Immunology Other Flavonoids Polyphenols
  4. Ophiopogon japonicus (L. f.) Ker-Gawl.
  5. Methylophiopogonone A

Methylophiopogonone A, a homoisoflavonoid isolated from the tuberous roots of Ophiopogon japonicas, shows anti-inflammatory activity.

For research use only. We do not sell to patients.

Methylophiopogonone A Chemical Structure

Methylophiopogonone A Chemical Structure

CAS No. : 74805-90-6

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 275 In-stock
Solution
10 mM * 1 mL in DMSO USD 275 In-stock
Solid
5 mg USD 250 In-stock
10 mg USD 400 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Methylophiopogonone A:

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  • Biological Activity

  • Purity & Documentation

  • References

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Description

Methylophiopogonone A, a homoisoflavonoid isolated from the tuberous roots of Ophiopogon japonicas, shows anti-inflammatory activity[1].

Molecular Weight

340.33

Formula

C19H16O6

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1C(CC2=CC=C(OCO3)C3=C2)=COC4=C(C)C(O)=C(C)C(O)=C14

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (293.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9383 mL 14.6916 mL 29.3832 mL
5 mM 0.5877 mL 2.9383 mL 5.8766 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  0.5% CMC-Na/saline water

    Solubility: 12.5 mg/mL (36.73 mM); Suspended solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.64%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9383 mL 14.6916 mL 29.3832 mL 73.4581 mL
5 mM 0.5877 mL 2.9383 mL 5.8766 mL 14.6916 mL
10 mM 0.2938 mL 1.4692 mL 2.9383 mL 7.3458 mL
15 mM 0.1959 mL 0.9794 mL 1.9589 mL 4.8972 mL
20 mM 0.1469 mL 0.7346 mL 1.4692 mL 3.6729 mL
25 mM 0.1175 mL 0.5877 mL 1.1753 mL 2.9383 mL
30 mM 0.0979 mL 0.4897 mL 0.9794 mL 2.4486 mL
40 mM 0.0735 mL 0.3673 mL 0.7346 mL 1.8365 mL
50 mM 0.0588 mL 0.2938 mL 0.5877 mL 1.4692 mL
60 mM 0.0490 mL 0.2449 mL 0.4897 mL 1.2243 mL
80 mM 0.0367 mL 0.1836 mL 0.3673 mL 0.9182 mL
100 mM 0.0294 mL 0.1469 mL 0.2938 mL 0.7346 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Methylophiopogonone A
Cat. No.:
HY-N2441
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