Metixene hydrochloride

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Metixene (Piperidine) hydrochloride hydrate is an anticholinergic and antiparkinsonian agent. Metixene hydrochloride potently inhibits binding of quinuclidinyl benzilate (QNB) with the muscarinic receptor, IC₅₀ and K_i values of 55 nM and 15 nM, respectively. Metixene hydrochloride can be used for the research of parkinsonian.

For research use only. We do not sell to patients.

Metixene hydrochloride Chemical Structure

CAS No. : 1553-34-0

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Other In-stock Forms of Metixene hydrochloride:

Metixene hydrochloride hydrate

Other Forms of Metixene hydrochloride:

Metixene hydrochloride hydrate In-stock
Metixene Get quote

1 Publications Citing Use of MCE Metixene hydrochloride

•bioRxiv. 2020 May.

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Description	Metixene (Piperidine) hydrochloride hydrate is an anticholinergic and antiparkinsonian agent. Metixene hydrochloride potently inhibits binding of quinuclidinyl benzilate (QNB) with the muscarinic receptor, IC₅₀ and K_i values of 55 nM and 15 nM, respectively. Metixene hydrochloride can be used for the research of parkinsonian^[1]^[2]^[3].
In Vitro	Metixene hydrochloride can potentially inhibit the binding of QNB with the muscarinic receptor， IC₅₀ and K_i values of 55 nM and 15 nM, respectively^[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Metixene hydrochloride Related Antibodies
Molecular Weight	345.93
Formula	C₂₀H₂₄ClNS
CAS No.	1553-34-0
SMILES	CN1CC(CC2C3=C(SC4=C2C=CC=C4)C=CC=C3)CCC1.[H]Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (269 KB) Handling Instructions (2659 KB)
References	[1]. Syvälahti EK, et al. Effects of antiparkinsonian drugs on muscarinic receptor binding in rat brain, heart and lung. Pharmacol Toxicol. 1988 Feb;62(2):90-4. [Content Brief] [2]. J. Hagenah, et al. Exogenous levodopa is not toxic to elderly subjects with non-parkinsonian movement disorders: further clinical evidence. , 106(3-4), 301–307. doi:10.1007/s007020050159 [3]. S L Levin, et al. Dualism in the effect of cholinolytics upon the human parotid gland deprived of parasympathetic control. Int J Clin Pharmacol Res. 1986;6(5):429-39. [Content Brief]