2. Metabolic Enzyme/Protease
  3. Hexokinase
  4. Metrizamide

Metrizamide  (Synonyms: Amipaque)

Cat. No.: HY-W000133 Purity: ≥99.0%
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Metrizamide (Amipaque) is used as the contrast medium for angiography in neuroradiological investigations. Metrizamide inhibits human brain hexokinase.

For research use only. We do not sell to patients.

Metrizamide Chemical Structure

Metrizamide Chemical Structure

CAS No. : 31112-62-6

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1 mg USD 330 In-stock
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Based on 1 publication(s) in Google Scholar

Metrizamide Related Antibodies

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Description

Metrizamide (Amipaque) is used as the contrast medium for angiography in neuroradiological investigations[1]. Metrizamide inhibits human brain hexokinase[2].

In Vitro

Metrizamide is a contrast medium possessing unique properties, one of which is that even in an isotonic solution it has a radiographic density sufficient for a diagnostic myelogram[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Metrizamide Related Antibodies
Molecular Weight

789.10

Formula

C18H22I3N3O8
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

IC(C(N(C)C(C)=O)=C1I)=C(C(N[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)OC2O)=O)C(I)=C1NC(C)=O
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (63.36 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2673 mL 6.3363 mL 12.6727 mL
5 mM 0.2535 mL 1.2673 mL 2.5345 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

V1

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (254 KB) Elemental Analysis Report (112 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.2673 mL 6.3363 mL 12.6727 mL 31.6817 mL
5 mM 0.2535 mL 1.2673 mL 2.5345 mL 6.3363 mL
10 mM 0.1267 mL 0.6336 mL 1.2673 mL 3.1682 mL
15 mM 0.0845 mL 0.4224 mL 0.8448 mL 2.1121 mL
20 mM 0.0634 mL 0.3168 mL 0.6336 mL 1.5841 mL
25 mM 0.0507 mL 0.2535 mL 0.5069 mL 1.2673 mL
30 mM 0.0422 mL 0.2112 mL 0.4224 mL 1.0561 mL
40 mM 0.0317 mL 0.1584 mL 0.3168 mL 0.7920 mL
50 mM 0.0253 mL 0.1267 mL 0.2535 mL 0.6336 mL
60 mM 0.0211 mL 0.1056 mL 0.2112 mL 0.5280 mL
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Metrizamide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Metrizamide31112-62-6AmipaqueHexokinasecontrast mediumangiographyneuroradiological investigationsmyelogramInhibitorinhibitorinhibit

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