2. Epigenetics
  3. METTL3
  4. METTL3-IN-2

METTL3-IN-2 (compound 28) is a METTL3 inhibitor with an IC50 value of 6.1 nM. METTL3-IN-2 inhibits cell proliferation of Caov3 cancer cells.

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METTL3-IN-2 Chemical Structure

METTL3-IN-2 Chemical Structure

CAS No. : 2767258-88-6

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METTL3-IN-2 Related Antibodies

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Description

METTL3-IN-2 (compound 28) is a METTL3 inhibitor with an IC50 value of 6.1 nM. METTL3-IN-2 inhibits cell proliferation of Caov3 cancer cells[1].

In Vitro

METTL3-IN-2 inhibits METTL3 activity with an IC50 value of 6.1 nM[1].
METTL3-IN-2 (0-30 μM; 120 h) inhibits cell proliferation of Caov3 cells[1].
METTL3-IN-2 (0-30 μM; 120 h) inhibits growth of KASUMI cells with an IC50 value of 315.8 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

METTL3-IN-2 Related Antibodies

Cell Proliferation Assay[1]

Cell Line: Caov3 cell line
Concentration: 0-30 μM
Incubation Time: 120 hours
Result: Inhibited cell proliferation of Caov3 cells with an IC50 value of 102.5 nM.
Molecular Weight

454.53

Formula

C25H26N8O
CAS No.
SMILES

COC1=CN2C(C(C3=CN(CC4=CN5C(C=CC(CNCC6(C7)CC7C6)=C5)=N4)N=N3)=C1)=CN=C2
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References
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METTL3-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

METTL3-IN-22767258-88-6METTL3Methyltransferase-like 3cell proliferationCaov3KASUMIheteroaromatic compoundInhibitorinhibitorinhibit

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HY-148468
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