1. Epigenetics
  2. MicroRNA
  3. microRNA-21-IN-2

microRNA-21-IN-2 is a potential miR-21 inhibitor with an AC50 value of 3.29 μM. microRNA-21-IN-2 can be used for the research of cancer.

For research use only. We do not sell to patients.

microRNA-21-IN-2 Chemical Structure

microRNA-21-IN-2 Chemical Structure

CAS No. : 303018-40-8

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5 mg USD 270 In-stock
10 mg USD 410 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

microRNA-21-IN-2 is a potential miR-21 inhibitor with an AC50 value of 3.29 μM. microRNA-21-IN-2 can be used for the research of cancer[1].

IC50 & Target

AC50: 3.29 μM (miR-21)[1]

In Vitro

microRNA-21-IN-2 can inhibit miR-21 activity with an AC50 value of 3.29 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

341.38

Formula

C17H15N3O3S

CAS No.
Appearance

Solid

Color

Light yellow to light brown

SMILES

O=C(NC1=CC=C(OCO2)C2=C1)CSC3=NC(C)=CC(C)=C3C#N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 9.09 mg/mL (26.63 mM; ultrasonic and warming and adjust pH to 3 with HCl and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9293 mL 14.6464 mL 29.2929 mL
5 mM 0.5859 mL 2.9293 mL 5.8586 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9293 mL 14.6464 mL 29.2929 mL 73.2322 mL
5 mM 0.5859 mL 2.9293 mL 5.8586 mL 14.6464 mL
10 mM 0.2929 mL 1.4646 mL 2.9293 mL 7.3232 mL
15 mM 0.1953 mL 0.9764 mL 1.9529 mL 4.8821 mL
20 mM 0.1465 mL 0.7323 mL 1.4646 mL 3.6616 mL
25 mM 0.1172 mL 0.5859 mL 1.1717 mL 2.9293 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
microRNA-21-IN-2
Cat. No.:
HY-151516
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