Miltipolone

Cat. No.: HY-N10796 Purity: 95.36%: FAQs
Data Sheet SDS COA Handling Instructions

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Miltipolone is a potent cytotoxic compound isolated from the fresh roots of Salvia divinorum.

For research use only. We do not sell to patients.

Miltipolone Chemical Structure

CAS No. : 131086-61-8

Size	Price	Stock	Quantity
1 mg	USD 360	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 897	In-stock	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Miltipolone is a potent cytotoxic compound isolated from the fresh roots of Salvia divinorum^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A-375	IC₅₀	3.5 μM Compound: 1, CCDC759536	Antiproliferative activity against human A375 cells after 96 hrs by MTT assay Antiproliferative activity against human A375 cells after 96 hrs by MTT assay	[PMID: 21296467]
A549	IC₅₀	1.92 μM Compound: 1, CCDC759536	Antiproliferative activity against human A549 cells after 96 hrs by MTT assay Antiproliferative activity against human A549 cells after 96 hrs by MTT assay	[PMID: 21296467]
Bel-7402	IC₅₀	0.9 μM Compound: 1, CCDC759536	Antiproliferative activity against human Bel7402 cells after 96 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 96 hrs by MTT assay	[PMID: 21296467]
HeLa	IC₅₀	1.44 μM Compound: 1, CCDC759536	Antiproliferative activity against human HeLa cells after 96 hrs by MTT assay Antiproliferative activity against human HeLa cells after 96 hrs by MTT assay	[PMID: 21296467]
HepG2	IC₅₀	2 μM Compound: 1, CCDC759536	Antiproliferative activity against human HepG2 cells after 96 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 96 hrs by MTT assay	[PMID: 21296467]
HT-1080	IC₅₀	1.36 μM Compound: 1, CCDC759536	Antiproliferative activity against human HT1080 cells after 96 hrs by MTT assay Antiproliferative activity against human HT1080 cells after 96 hrs by MTT assay	[PMID: 21296467]
HUVEC	IC₅₀	20 μM Compound: 1, CCDC759536	Antiproliferative activity against human HUVEC cells after 96 hrs by MTT assay Antiproliferative activity against human HUVEC cells after 96 hrs by MTT assay	[PMID: 21296467]
Jurkat	IC₅₀	1.4 μM Compound: 1, CCDC759536	Antiproliferative activity against human Jurkat cells after 96 hrs by MTT assay Antiproliferative activity against human Jurkat cells after 96 hrs by MTT assay	[PMID: 21296467]
MCF7	IC₅₀	2 μM Compound: 1, CCDC759536	Antiproliferative activity against human MCF7 cells after 96 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 96 hrs by MTT assay	[PMID: 21296467]
NCI-N87	IC₅₀	1.6 μM Compound: 1, CCDC759536	Antiproliferative activity against human NCI-N87 cells after 96 hrs by MTT assay Antiproliferative activity against human NCI-N87 cells after 96 hrs by MTT assay	[PMID: 21296467]
PANC-1	IC₅₀	5.95 μM Compound: 1, CCDC759536	Antiproliferative activity against human PANC1 cells after 96 hrs by MTT assay Antiproliferative activity against human PANC1 cells after 96 hrs by MTT assay	[PMID: 21296467]

Molecular Weight

300.39

Formula

C₁₉H₂₄O₃

CAS No.

131086-61-8

Appearance

Solid

Color

Yellow to brown

SMILES

O=C1C=C2C([C@@H]3CC4C(C)(C)CCC[C@]24CO3)=CC(C)=C1O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Purity: 95.36%

Select Batch:

Data Sheet (272 KB) SDS (251 KB)

COA (259 KB) LCMS (77 KB)

Handling Instructions (2659 KB)

References

[1]. Haro Ginda, et al. Miltipolone, a New Diterpenoid Tropolone Possessing Cytotoxic Activities from Salvia miltiorrhiza Bunge. Chemistry Letters 1990, Vol.19, No.9.

Miltipolone Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Miltipolone131086-61-8OthersSalvia divinorumcytotoxicInhibitorinhibitorinhibit

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Miltipolone

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