(-)-(S)-Cibenzoline-d₄ (Synonyms: Escibenzoline-d₄; (-)-(S)-Cifenline-d₄; (-)-(S)-Ro 22-7796-d₄)

Cat. No.: HY-106577AS: FAQs
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(-)-(S)-Cibenzoline-d₄ (Escibenzoline-d₄) is deuterium labeled (-)-(S)-Cibenzoline. (-)-(S)-Cibenzoline (Escibenzoline), a S(+)-enantiomer of Cibenzoline, is an antiarrhythmic agent.

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(-)-(S)-Cibenzoline-d<sub>4</sub> Chemical Structure

(-)-(S)-Cibenzoline-d₄ Chemical Structure

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Other Forms of (-)-(S)-Cibenzoline-d₄:

(-)-(S)-Cibenzoline Get quote
R-(+)-Cibenzoline-d₄ Get quote

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Description	(-)-(S)-Cibenzoline-d₄ (Escibenzoline-d₄) is deuterium labeled (-)-(S)-Cibenzoline. (-)-(S)-Cibenzoline (Escibenzoline), a S(+)-enantiomer of Cibenzoline, is an antiarrhythmic agent^[1]^[2].
Molecular Weight	266.37
Formula	C₁₈H₁₄D₄N₂
Unlabeled CAS	103419-18-7
SMILES	[2H]C1([2H])C([2H])([2H])N=C([C@@H]2C(C3=CC=CC=C3)(C4=CC=CC=C4)C2)N1
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (273 KB) Handling Instructions (2659 KB)
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief] [2]. T Niwa, et al. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A. Drug Metab Dispos. 2000 Sep;28(9):1128-34. [Content Brief]

(-)-(S)-Cibenzoline-d₄ Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(-)-(S)-Cibenzoline-d₄Escibenzoline-d₄ (-)-(S)-Cifenline-d₄ (-)-(S)-Ro 22-7796-d₄Potassium ChannelIsotope-Labeled CompoundsKcsAInhibitorinhibitorinhibit

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(-)-(S)-Cibenzoline-d4 (Synonyms: Escibenzoline-d4; (-)-(S)-Cifenline-d4; (-)-(S)-Ro 22-7796-d4)

Other Forms of (-)-(S)-Cibenzoline-d4:

(-)-(S)-Cibenzoline-d4 Related Antibodies

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(-)-(S)-Cibenzoline-d4 Related Classifications