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Mip-IN-1（S,S-28i）is a new rapamycin-derived macrophage infectivity potentiator (Mip) inhibitor. Mip-IN-1 displays strong anti-enzymatic activity against the Mip proteins of Neisseria meningitidis and Neisseria gonorrhoeae and substantially improved the ability of macrophages to kill the bacteria.

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Mip-IN-1 Chemical Structure

Mip-IN-1 Chemical Structure

CAS No. : 2984599-57-5

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Description

Mip-IN-1（S,S-28i）is a new rapamycin-derived macrophage infectivity potentiator (Mip) inhibitor. Mip-IN-1 displays strong anti-enzymatic activity against the Mip proteins of Neisseria meningitidis and Neisseria gonorrhoeae and substantially improved the ability of macrophages to kill the bacteria[1].

Molecular Weight

524.61

Formula

C27H29FN4O4S
CAS No.
SMILES

O=C([C@@H](NC([C@H]1N(CCCC1)S(=O)(CC2=CC=CC=C2)=O)=O)C3=CC=C(C=C3)F)NCC4=CN=CC=C4
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Mip-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mip-IN-12984599-57-5Othersmacrophage infectivity potentiator (Mip)Neisseria meningitidesNeisseria gonorrhoeaebacteriainfectionInhibitorinhibitorinhibit

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