2. Anti-infection
  3. Bacterial Parasite
  4. Misonidazole

Misonidazole (Ro 7-0582; SR 1354) is a hypoxic tumor cell radiosensitizer. Misonidazole also has antimicrobial effects.

For research use only. We do not sell to patients.

Misonidazole Chemical Structure

Misonidazole Chemical Structure

CAS No. : 13551-87-6

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Based on 1 publication(s) in Google Scholar

Misonidazole Related Antibodies

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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Description

Misonidazole (Ro 7-0582; SR 1354) is a hypoxic tumor cell radiosensitizer[1]. Misonidazole also has antimicrobial effects[2].

Cellular Effect
Cell Line Type Value Description References
CHO-AA8 IC50
12080 μM
Compound: 1 (misonidazole)
Growth inhibition in CHO subline AA8 cells exposed for 18 hr under aerobic(air) conditions
Growth inhibition in CHO subline AA8 cells exposed for 18 hr under aerobic(air) conditions
[PMID: 1479583]
HCT-116 IC50
0.53 mM
Compound: 1
Cytotoxicity against human HCT116 cells incubated for 4 hrs under anaerobic condition measured after 5 days by sulforhodamine B assay
Cytotoxicity against human HCT116 cells incubated for 4 hrs under anaerobic condition measured after 5 days by sulforhodamine B assay
[PMID: 29253343]
Molecular Weight

201.18

Formula

C7H11N3O4
CAS No.
Appearance

Solid

Color

Off-white to yellow

SMILES

COCC(O)CN1C([N+]([O-])=O)=NC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 98.74%

SDS (393 KB)

COA (255 KB)

Handling Instructions (2659 KB)
References
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Misonidazole Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Misonidazole13551-87-6Ro 7-0582 SR 1354SR1354SR 1354SR-1354BacterialParasiteradiation sensitizerantimicrobialantiprotozoalInhibitorinhibitorinhibit

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