Mitotane (Standard)

Cat. No.: HY-13690R Purity: ≥98%: FAQs
Handling Instructions

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Mitotane (Standard) is the analytical standard of Mitotane. This product is intended for research and analytical applications. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions.

For research use only. We do not sell to patients.

Mitotane (Standard) Chemical Structure

CAS No. : 53-19-0

Size	Price	Stock	Quantity
10 mg	USD 30	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 55	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 83	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 125	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Description	Mitotane (Standard) is the analytical standard of Mitotane . This product is intended for research and analytical applications. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions.
Molecular Weight	320.04
Formula	C₁₄H₁₀Cl₄
CAS No.	53-19-0
Appearance	Solid
Color	White to off-white
SMILES	ClC1=CC=C(C(C2=CC=CC=C2Cl)C(Cl)Cl)C=C1
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Mitotane (Standard) Related Classifications

Molarity Calculator
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mitotane (Standard)53-19-0Apoptosisantineoplasticadrenocortical carcinomacholesterolcorticotroph cellsdrug-drug interactionsH295RTαT1HepaRGInhibitorinhibitorinhibit

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Mitotane (Standard)

Product Information

Purity & Documentation

Customer Review