2. Stem Cell/Wnt
  3. Wnt
  4. ML243

ML243 is a selective small-molecule inhibitor of breast cancer stem cells. ML243 has 32-fold greater selective inhibition in the breast CSC-like cell line HMLE_shECad than the control cell line HMLE_shGFP.

For research use only. We do not sell to patients.

ML243 Chemical Structure

ML243 Chemical Structure

CAS No. : 1426576-80-8

Size Price Stock Quantity
1 mg Get quote 3 - 4 weeks 4 - 5 weeks 2 - 3 weeks
5 mg   Get quote  
10 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

ML243 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

ML243 is a selective small-molecule inhibitor of breast cancer stem cells. ML243 has 32-fold greater selective inhibition in the breast CSC-like cell line HMLE_shECad than the control cell line HMLE_shGFP[1].

IC50 & Target

Breast CSCs[1]
Cellular Effect
Cell Line Type Value Description References
HMLE EC50
2 μM
Compound: 19d, ML243
Cytotoxicity against human CSC-like HMLE cells expressing shRNA and epithelial cadherin after 70 to 74 hrs by Cell Titer Glo assay
Cytotoxicity against human CSC-like HMLE cells expressing shRNA and epithelial cadherin after 70 to 74 hrs by Cell Titer Glo assay
[PMID: 23403082]
HMLE EC50
63.98 μM
Compound: 19d, ML243
Cytotoxicity against human HMLE cells expressing shRNA and GFP after 70 to 74 hrs by Cell Titer Glo assay
Cytotoxicity against human HMLE cells expressing shRNA and GFP after 70 to 74 hrs by Cell Titer Glo assay
[PMID: 23403082]
Molecular Weight

260.35

Formula

C14H16N2OS
CAS No.
SMILES

CCC1=CC=C(/C=C/C(NC2=NCCS2)=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

ML243 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ML2431426576-80-8ML 243ML-243WntBreast cancerHMLE_shECadHMLE_shGFPInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
ML243
Cat. No.:
HY-19972
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (0 KB) Français - FR (0 KB) Deutsch - DE (0 KB) Norwegian - NO (0 KB) Español - ES (0 KB) Swedish - SV (0 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.