1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. ML262

ML-262 is an inhibitor of hepatic lipid droplet formation (IC50=6.4 nM in murine AML-12 cells), which is associated with non-alcoholic fatty liver disease.1 ML-262 does not induce cytotoxicity (up to 33 μM) or inhibit fatty acid uptake (up to 50 μM).

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ML262 Chemical Structure

ML262 Chemical Structure

CAS No. : 902502-82-3

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Description

ML-262 is an inhibitor of hepatic lipid droplet formation (IC50=6.4 nM in murine AML-12 cells), which is associated with non-alcoholic fatty liver disease.1 ML-262 does not induce cytotoxicity (up to 33 μM) or inhibit fatty acid uptake (up to 50 μM).

Molecular Weight

480.62

Formula

C27H32N2O4S

CAS No.
SMILES

O=C(C1=CC(C2=CC=CC=C2)=C(N3CCOCC3)S1)NCCC4=CC=C(OCC)C(OCC)=C4

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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ML262
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HY-111180
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