2. Metabolic Enzyme/Protease
  3. Phospholipase
  4. ML299

ML299 is a selective allosteric modulator and a dual inhibitor of phospholipases D1 and D2 (IC50 values are 6 and 12 nM, respectively). ML299 decreases invasive migration in U87-MG glioblastoma cells.

For research use only. We do not sell to patients.

ML299 Chemical Structure

ML299 Chemical Structure

CAS No. : 1426916-00-8

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500 μg USD 132 Get quote 3 - 4 weeks 4 - 5 weeks 2 - 3 weeks
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ML299 Related Antibodies

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Description

ML299 is a selective allosteric modulator and a dual inhibitor of phospholipases D1 and D2 (IC50 values are 6 and 12 nM, respectively). ML299 decreases invasive migration in U87-MG glioblastoma cells[1].

Cellular Effect
Cell Line Type Value Description References
Calu-1 IC50
0.01 μM
Compound: 3; ML299
Antiproliferative activity against human Calu-1 cells assessed as reduction on cell viability by cellular assay
Antiproliferative activity against human Calu-1 cells assessed as reduction on cell viability by cellular assay
[PMID: 35450377]
Molecular Weight

489.38

Formula

C23H26BrFN4O2
CAS No.
SMILES

O=C(C1=CC=C(C=C1)Br)N[C@H](CN2CCC3(N(CNC3=O)C4=CC=CC(F)=C4)CC2)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ML299 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ML2991426916-00-8ML 299ML-299PhospholipaseInhibitorinhibitorinhibit

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