2. Metabolic Enzyme/Protease
  3. Lipoxygenase
  4. MLS000536924

MLS000536924 is a potent and selective inhibitor of human epithelial 15-lipoxygenase-2 with competitive activity. MLS000536924 exhibits more than 50-fold selectivity in inhibiting h15-LOX-2 and can be effectively applied to study its role in atherosclerosis, cystic fibrosis, and ferroptosis. The binding mode of MLS000536924 shows stronger restriction of protein movement than other inhibitors, further verifying its higher biological activity.

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MLS000536924 Chemical Structure

MLS000536924 Chemical Structure

CAS No. : 511306-37-9

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MLS000536924 Related Antibodies

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Description

MLS000536924 is a potent and selective inhibitor of human epithelial 15-lipoxygenase-2 with competitive activity. MLS000536924 exhibits more than 50-fold selectivity in inhibiting h15-LOX-2 and can be effectively applied to study its role in atherosclerosis, cystic fibrosis, and ferroptosis. The binding mode of MLS000536924 shows stronger restriction of protein movement than other inhibitors, further verifying its higher biological activity[1].

Molecular Weight

281.38

Formula

C16H15N3S
CAS No.
SMILES

CC1=CC=C(C=C1)CSC2=NN(C=N2)C3=CC=CC=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MLS000536924 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MLS000536924511306-37-9MLS 000536924MLS-000536924LipoxygenaseLOXInhibitorinhibitorinhibit

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HY-116919
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