1. Metabolic Enzyme/Protease
  2. MMP
  3. MMP-2/9-IN-1

MMP-2/9-IN-1 (Compound 4a) is a potent dual MMP-2 and MMP-9 inhibitor with IC50 values of 56 nM and 38 nM, respectively. MMP-2/9-IN-1 inhibits tumor growth, strongly induces cancer cell apoptosis, inhibits cell migration, and suppresses cell cycle progression leading to DNA fragmentation.

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MMP-2/9-IN-1 Chemical Structure

MMP-2/9-IN-1 Chemical Structure

CAS No. : 2415311-84-9

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Description

MMP-2/9-IN-1 (Compound 4a) is a potent dual MMP-2 and MMP-9 inhibitor with IC50 values of 56 nM and 38 nM, respectively. MMP-2/9-IN-1 inhibits tumor growth, strongly induces cancer cell apoptosis, inhibits cell migration, and suppresses cell cycle progression leading to DNA fragmentation[1].

IC50 & Target

MMP-9

38 nM (IC50)

MMP-2

56 nM (IC50)

Molecular Weight

441.29

Formula

C14H16IN7S

CAS No.
SMILES

C/C(C1=C(C)N=C(N/N=C/C2=CC=C(I)C=C2)S1)=N\NC(N)=N

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Product Name:
MMP-2/9-IN-1
Cat. No.:
HY-147867
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