2. Metabolic Enzyme/Protease
  3. MMP
  4. MMP-2/9-IN-1

MMP-2/9-IN-1 (Compound 4a) is a potent dual MMP-2 and MMP-9 inhibitor with IC50 values of 56 nM and 38 nM, respectively. MMP-2/9-IN-1 inhibits tumor growth, strongly induces cancer cell apoptosis, inhibits cell migration, and suppresses cell cycle progression leading to DNA fragmentation.

For research use only. We do not sell to patients.

MMP-2/9-IN-1 Chemical Structure

MMP-2/9-IN-1 Chemical Structure

CAS No. : 2415311-84-9

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MMP-2/9-IN-1 Related Antibodies

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MMP-1 MMP-2 MMP-3 MMP-8 MMP-9 MMP-13 MMP-14 MMP-17 ADAM10 ADAM17 MMP-7 MMP-12 MMP-10 MMP ADAM8

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Description

MMP-2/9-IN-1 (Compound 4a) is a potent dual MMP-2 and MMP-9 inhibitor with IC50 values of 56 nM and 38 nM, respectively. MMP-2/9-IN-1 inhibits tumor growth, strongly induces cancer cell apoptosis, inhibits cell migration, and suppresses cell cycle progression leading to DNA fragmentation[1].

IC50 & Target

MMP-9

38 nM (IC50)

MMP-2

56 nM (IC50)

Molecular Weight

441.29

Formula

C14H16IN7S
CAS No.
SMILES

C/C(C1=C(C)N=C(N/N=C/C2=CC=C(I)C=C2)S1)=N\NC(N)=N
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MMP-2/9-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MMP-2/9-IN-12415311-84-9MMPMatrix metalloproteinasesMDA-MB-231HCT-116MCF-7anticancerInhibitorinhibitorinhibit

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