2. Metabolic Enzyme/Protease
  3. MMP
  4. MMP13-IN-4

MMP13-IN-4 (compound 13) is a potent and selective inhibitor of MMP-13 (IC50=14.6 μM)，involved in osteoarthritis (OA).

For research use only. We do not sell to patients.

MMP13-IN-4 Chemical Structure

MMP13-IN-4 Chemical Structure

CAS No. : 514855-02-8

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MMP13-IN-4 Related Antibodies

Top Publications Citing Use of Products

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View All Isoforms
MMP-1 MMP-2 MMP-3 MMP-8 MMP-9 MMP-13 MMP-14 MMP-17 ADAM10 ADAM17 MMP-7 MMP-12 MMP-10 MMP ADAM8

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Description

MMP13-IN-4 (compound 13) is a potent and selective inhibitor of MMP-13 (IC50=14.6 μM)，involved in osteoarthritis (OA)[1].

IC50 & Target

IC50: 91 μM (MMP-1), 99 μM (MMP-2), 68 μM (MMP-9), 14.6 μM (MMP-13), 63 μM (MMP-14)[1]
Molecular Weight

485.29

Formula

C21H17BrN4O5
CAS No.
SMILES

O=C(N/N=C(C1=CC=C(NC(C2=CC=C(Br)O2)=O)C=C1)\C)CC3=CC=C([N+]([O-])=O)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MMP13-IN-4 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MMP13-IN-4514855-02-8MMPMatrix metalloproteinasesInhibitorinhibitorinhibit

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Product Name:
MMP13-IN-4
Cat. No.:
HY-149377
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