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  5. Monensin B

Monensin B is a polyketide produced by Streptomyces cinnamonensis. Fermentations of Streptomyces cinnamonensis produce a mixture of Monensin A and Monensin B in a ratio dependent upon the relative concentrations of ethylmalonyl-CoA and methylmalonyl-CoA.

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Monensin B Chemical Structure

Monensin B Chemical Structure

CAS No. : 30485-16-6

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Based on 1 publication(s) in Google Scholar

Monensin B Related Antibodies

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Description

Monensin B is a polyketide produced by Streptomyces cinnamonensis. Fermentations of Streptomyces cinnamonensis produce a mixture of Monensin A and Monensin B in a ratio dependent upon the relative concentrations of ethylmalonyl-CoA and methylmalonyl-CoA[1].

Molecular Weight

656.84

Formula

C35H60O11
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@]1([C@]2([H])O[C@@](CC2)([C@]3([H])O[C@]([C@@]4([H])O[C@](O)([C@@H](C[C@@H]4C)C)CO)([H])C[C@@H]3C)C)O[C@@]5(CC1)O[C@]([C@@H]([C@H](C5)O)C)([H])[C@@H](C)[C@@H](OC)[C@H](C)C(O)=O
Structure Classification
Initial Source

Streptomyces cinnamonensis C730.1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

Ethanol : 100 mg/mL (152.24 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5224 mL 7.6122 mL 15.2244 mL
5 mM 0.3045 mL 1.5224 mL 3.0449 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.00%

SDS (252 KB)

COA (262 KB) HNMR (321 KB) RP-HPLC (178 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 1.5224 mL 7.6122 mL 15.2244 mL 38.0610 mL
5 mM 0.3045 mL 1.5224 mL 3.0449 mL 7.6122 mL
10 mM 0.1522 mL 0.7612 mL 1.5224 mL 3.8061 mL
15 mM 0.1015 mL 0.5075 mL 1.0150 mL 2.5374 mL
20 mM 0.0761 mL 0.3806 mL 0.7612 mL 1.9031 mL
25 mM 0.0609 mL 0.3045 mL 0.6090 mL 1.5224 mL
30 mM 0.0507 mL 0.2537 mL 0.5075 mL 1.2687 mL
40 mM 0.0381 mL 0.1903 mL 0.3806 mL 0.9515 mL
50 mM 0.0304 mL 0.1522 mL 0.3045 mL 0.7612 mL
60 mM 0.0254 mL 0.1269 mL 0.2537 mL 0.6344 mL
80 mM 0.0190 mL 0.0952 mL 0.1903 mL 0.4758 mL
100 mM 0.0152 mL 0.0761 mL 0.1522 mL 0.3806 mL
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Monensin B Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Monensin B30485-16-6OthersCoAfermentationsInhibitorinhibitorinhibit

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