2. Metabolic Enzyme/Protease
  3. Liposome
  4. mono-Pal-MTO

mono-Pal-MTO is a palm oil-based lipid produced by combining the anticancer agent mitoxantrone (MTO) with palmitoleic acid. When nanoparticles of mono-Pal-MTO and di-Pal-MTO are combined in a molar ratio of 1:1, they show effective siRNA cell delivery and enhance anticancer activity.

For research use only. We do not sell to patients.

mono-Pal-MTO Chemical Structure

mono-Pal-MTO Chemical Structure

CAS No. : 1349197-89-2

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Based on 1 publication(s) in Google Scholar

mono-Pal-MTO Related Antibodies

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Description

mono-Pal-MTO is a palm oil-based lipid produced by combining the anticancer agent mitoxantrone (MTO) with palmitoleic acid. When nanoparticles of mono-Pal-MTO and di-Pal-MTO are combined in a molar ratio of 1:1, they show effective siRNA cell delivery and enhance anticancer activity[1].

In Vitro

Delivery of Mcl-1-specific anticancer siRNA (siMcl-1) using nanoparticles of mono-Pal-MTO and di-Pal-MTO (md11-Pal-MTO) in a 1:1 molar ratio enhances in vitro antitumour activity, reducing tumour cell viability by 81% and tumour size by 83%. Lipofectamine 2000-mediated transfection with siMcl-1 reduces tumour cell viability by 68%[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

mono-Pal-MTO Related Antibodies
Molecular Weight

680.87

Formula

C38H56N4O7
CAS No.
SMILES

CCCCCC/C=C\CCCCCCCC(OCCNCCNC1=C2C(C(C3=C(O)C=CC(O)=C3C2=O)=O)=C(C=C1)NCCNCCO)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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mono-Pal-MTO Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

mono-Pal-MTO1349197-89-2Liposomemitoxantronepalmitoleic acidsiRNAanticancerInhibitorinhibitorinhibit

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