Monodes(N-carboxymethyl)valine Daclatasvir (Synonyms: Daclatasvir Impurity A)

Cat. No.: HY-133246: FAQs
Data Sheet Handling Instructions

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Monodes(N-carboxymethyl)valine Daclatasvir (Daclatasvir Impurity A) is the main degradation product of Daclatasvir. Daclatasvir is a potent HCV NS5A protein inhibitor.

For research use only. We do not sell to patients.

Monodes(N-carboxymethyl)valine Daclatasvir Chemical Structure

CAS No. : 1007884-60-7

Size	Price	Stock
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 512	Ask For Quote & Lead Time
Solution
10 mM * 1 mL in DMSO	USD 512	Ask For Quote & Lead Time
Solid
5 mg	USD 400	Ask For Quote & Lead Time
10 mg	USD 680	Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

Other Forms of Monodes(N-carboxymethyl)valine Daclatasvir:

Monodes(N-carboxymethyl)valine Daclatasvir TFA Get quote

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Description

Monodes(N-carboxymethyl)valine Daclatasvir (Daclatasvir Impurity A) is the main degradation product of Daclatasvir. Daclatasvir is a potent HCV NS5A protein inhibitor^[1].

Molecular Weight

581.71

Formula

C₃₃H₃₉N₇O₃

CAS No.

1007884-60-7

Appearance

Solid

Color

White to off-white

SMILES

COC(N[C@@H](C(C)C)C(N(CCC1)[C@@H]1C2=NC(C3=CC=C(C4=CC=C(C5=CNC([C@H]6NCCC6)=N5)C=C4)C=C3)=CN2)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL (429.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.7191 mL	8.5953 mL	17.1907 mL
5 mM	0.3438 mL	1.7191 mL	3.4381 mL
10 mM	0.1719 mL	0.8595 mL	1.7191 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Naz A , et al. Simultaneous analysis of daclatasvir with its three organic impurities: Application in stability studies, pharmaceutical and serum samples[J]. Microchemical Journal, 2019.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.7191 mL	8.5953 mL	17.1907 mL	42.9767 mL
	5 mM	0.3438 mL	1.7191 mL	3.4381 mL	8.5953 mL
	10 mM	0.1719 mL	0.8595 mL	1.7191 mL	4.2977 mL
	15 mM	0.1146 mL	0.5730 mL	1.1460 mL	2.8651 mL
	20 mM	0.0860 mL	0.4298 mL	0.8595 mL	2.1488 mL
	25 mM	0.0688 mL	0.3438 mL	0.6876 mL	1.7191 mL
	30 mM	0.0573 mL	0.2865 mL	0.5730 mL	1.4326 mL
	40 mM	0.0430 mL	0.2149 mL	0.4298 mL	1.0744 mL
	50 mM	0.0344 mL	0.1719 mL	0.3438 mL	0.8595 mL
	60 mM	0.0287 mL	0.1433 mL	0.2865 mL	0.7163 mL
	80 mM	0.0215 mL	0.1074 mL	0.2149 mL	0.5372 mL
	100 mM	0.0172 mL	0.0860 mL	0.1719 mL	0.4298 mL

Monodes(N-carboxymethyl)valine Daclatasvir Related Classifications

Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Monodes(N-carboxymethyl)valine Daclatasvir1007884-60-7Daclatasvir Impurity AHCVHepatitis C virusdegradationproductInhibitorinhibitorinhibit

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