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Moveltipril calcium  (Synonyms: MC-838 calcium)

Cat. No.: HY-105572
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Moveltipril calcium (MC-838 calcium) is an orally active angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moveltipril calcium binds via a stable thioester bond and exhibits relative resistance to enzymatic hydrolysis in rat liver homogenate. Moveltipril calcium effectively inhibits ACE extracted from rabbit lung in a concentration-dependent manner. Moveltipril calcium is able to highly specifically inhibit the contractile response to angiotensin-I (AI) in free rat aortic rings and guinea pig ileum preparations, while enhancing the contractile response to calcitonin.

For research use only. We do not sell to patients.

Moveltipril calcium Chemical Structure

Moveltipril calcium Chemical Structure

CAS No. : 85921-53-5

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Description

Moveltipril calcium (MC-838 calcium) is an orally active angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moveltipril calcium binds via a stable thioester bond and exhibits relative resistance to enzymatic hydrolysis in rat liver homogenate. Moveltipril calcium effectively inhibits ACE extracted from rabbit lung in a concentration-dependent manner. Moveltipril calcium is able to highly specifically inhibit the contractile response to angiotensin-I (AI) in free rat aortic rings and guinea pig ileum preparations, while enhancing the contractile response to calcitonin[1].

Molecular Weight

417.51

Formula

C19H29CaN2O5S.1/2Ca
CAS No.
SMILES

O=C(C1CCCCC1)N[C@H](C)C(SC[C@@H](C)C(N2[C@@H](CCC2)C([O-])=O)=O)=O.[0.5].[Ca+2]
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Moveltipril calcium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Moveltipril85921-53-5MC-838MC838MC 838OthersInhibitorinhibitorinhibit

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