1. Autophagy Apoptosis Immunology/Inflammation Cell Cycle/DNA Damage Membrane Transporter/Ion Channel Neuronal Signaling
  2. FKBP Calcium Channel
  3. MP-010

MP-010 is a FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. MP-010 promotes functional improvement in SOD1G93A amyotrophic lateral sclerosis (ALS) mice, as evidenced by improved motor coordination, increased integrity of neuromuscular junctions, and significantly enhanced survival of spinal motor neurons. MP-010 can be used for research in the field of neurological diseases.

For research use only. We do not sell to patients.

MP-010 Chemical Structure

MP-010 Chemical Structure

CAS No. : 3024617-59-9

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Description

MP-010 is a FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. MP-010 promotes functional improvement in SOD1G93A amyotrophic lateral sclerosis (ALS) mice, as evidenced by improved motor coordination, increased integrity of neuromuscular junctions, and significantly enhanced survival of spinal motor neurons. MP-010 can be used for research in the field of neurological diseases[1].

Molecular Weight

308.40

Formula

C14H20N4O2S

CAS No.
SMILES

CN(C)CCN1N=NC(CS(C2=CC=C(OC)C=C2)=O)=C1

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MP-010
Cat. No.:
HY-172152
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