2. GPCR/G Protein Neuronal Signaling
  3. Melanocortin Receptor
  4. MPCI

MPCI is a cell-permeant MC4R-selective ligand with pharmacological chaperone activity. MPCI is a MC4R antagonist with a Ki value of 0.218 μM on HEK293 cells expressing hMC4R. MPCI can be used for the research of MC4R-deficient obesity.

For research use only. We do not sell to patients.

MPCI Chemical Structure

MPCI Chemical Structure

CAS No. : 884538-31-2

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MPCI Related Antibodies

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Description

MPCI is a cell-permeant MC4R-selective ligand with pharmacological chaperone activity. MPCI is a MC4R antagonist with a Ki value of 0.218 μM on HEK293 cells expressing hMC4R. MPCI can be used for the research of MC4R-deficient obesity[1].

IC50 & Target

Ki: 0.218 μM (HEK293 cells expressing hMC4R)[1].
Molecular Weight

519.45

Formula

C25H32BrFN4O2
CAS No.
SMILES

O=C(C1=CC=CC(F)=C1CCC2=CC(Br)=CC=C2OC)NC(NCC3CCN(CC3)CC)=N
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MPCI Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MPCI884538-31-2Melanocortin ReceptorMC Receptorcell-permeantMC4R-selective ligandpharmacological chaperone activityHEK293 cellsMC4R-deficient obesityInhibitorinhibitorinhibit

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