2. Cell Cycle/DNA Damage Cytoskeleton Apoptosis Metabolic Enzyme/Protease
  3. Microtubule/Tubulin Apoptosis Caspase Mitochondrial Metabolism
  4. MPT0B214

MPT0B214 is a microtubule inhibitor that strongly binds to the colchicine binding site of tubulin, preventing tubulin polymerization. MPT0B214 induces apoptosis through a mitochondrial/caspase 9 dependent pathway and shows cytotoxicity across various human tumor cell lines. MPT0B214 can be used for cancer research.

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MPT0B214 Chemical Structure

MPT0B214 Chemical Structure

CAS No. : 1215208-65-3

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MPT0B214 Related Antibodies

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Description

MPT0B214 is a microtubule inhibitor that strongly binds to the colchicine binding site of tubulin, preventing tubulin polymerization. MPT0B214 induces apoptosis through a mitochondrial/caspase 9 dependent pathway and shows cytotoxicity across various human tumor cell lines. MPT0B214 can be used for cancer research[1].
Molecular Weight

368.38

Formula

C20H20N2O5
CAS No.
SMILES

O=C(C1=CC(OC)=C(C(OC)=C1)OC)C2=NC3=CC=C(C(N)=C3C=C2)OC
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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MPT0B214 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MPT0B2141215208-65-3Microtubule/TubulinApoptosisCaspaseMitochondrial Metabolismmicrotubulecaspase 9apoptosiscytotoxicityInhibitorinhibitorinhibit

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