Caspase Inhibitors

Caspase 1

Caspase 2

Caspase 3

Caspase 4

Caspase 5

Caspase 6

Caspase 7

Caspase 8

Caspase 9

Caspase 10

Caspase 12

Caspase

Caspase 11

Caspase-13

Caspase Inducers, Inhibitors, Activators, Modulators & Chemicals

Product Name	Caspase 1	Caspase 2	Caspase 3	Caspase 4	Caspase 5	Caspase 6	Caspase 7	Caspase 8	Caspase 9	Caspase 10	Caspase 12	Caspase	Caspase 11	Caspase-13	Purity
Z-VAD-FMK												Caspase			99.78%
Q-VD-OPh	Caspase-1, IC₅₀: 25-400 nM		Caspase-3, IC₅₀: 25-400 nM				Caspase-7, IC₅₀: 48 nM	Caspase-8, IC₅₀: 25-400 nM	Caspase-9, IC₅₀: 25-400 nM	Caspase-10, IC₅₀: 25-400 nM	Caspase-12, IC₅₀: 25-400 nM				99.78%
Z-VAD(OMe)-FMK												Caspase			98.20%
Sulforaphane			Caspase-3												99.75%
Belnacasan	Caspase-1														99.99%
(Rac)-M826			Caspase 3, IC₅₀: 0.005 μM
Z-DEVD-FMK			Caspase-3, IC₅₀: 18 μM												≥98.0%
Emricasan												Caspase			99.59%
Tauroursodeoxycholate			Caspase-3								Caspase-12				99.91%
Oxidopamine hydrobromide			Caspase-3					Caspase-8	Caspase-9						99.95%
Z-IETD-FMK								Caspase-8							≥98.0%
Ac-YVAD-cmk	Caspase-1														98.94%
Oxidopamine hydrochloride			Caspase-3					Caspase-8	Caspase-9						99.91%
Chlorin e6			Caspase 3												98.31%
Raptinal			Caspase 3												≥98.0%
Tauroursodeoxycholate sodium			Caspase-3								Caspase-12				98.88%
Ac-DEVD-CHO	Caspase-1, Ki: 18 nM	Caspase-2, Ki: 1710 nM	Caspase 3, Ki: 0.23 nM	Caspase-4, Ki: 132 nM	Caspase-5, Ki: 205 nM	Caspase-6, Ki: 31 nM	Caspase-7, Ki: 1.6 nM	Caspase-8, Ki: 0.92 nM	Caspase-9, Ki: 60 nM	Caspase-10, Ki: 12 nM					99.94%
Guggulsterone												Caspase			99.95%
Wedelolactone													Caspase-11		99.91%
Benzbromarone			Caspase 3					Caspase-8	Caspase 9						99.81%
Fucoxanthin			Caspase 3					Caspase-8	Caspase 9						99.47%
Ginsenoside Rh2								Caspase-8	Caspase-9						98.87%
Digitoxin			Caspase 3						Caspase-9						99.36%
BOC-D-FMK												Caspase
PAC-1			Procaspase-3, EC₅₀: 2.08 μM												99.93%
Terfenadine		Caspase-2		Caspase-4					Caspase-9						99.91%
Dehydrocorydaline							Caspase-7	Caspase-8							99.77%
VRT-043198	Caspase-1, Ki: 0.8 nM			Caspase-4, Ki: 0.6 nM
Ac-FLTD-CMK	Caspase-1, IC₅₀: 46.7 nM			Caspase-4, IC₅₀: 1.49 μM	Caspase-5, IC₅₀: 329 nM										99.53%
Z-YVAD-FMK												Caspase			≥98.0%
Dynorphin A			Caspase 3												98.06%
RGD peptide (GRGDNP)			Caspase 3												99.63%
Dihydrocapsaicin			Caspase 3												99.86%
Z-LEHD-FMK									Caspase-9						≥98.0%
Hydralazine hydrochloride			Caspase 3					Caspase-8	Caspase-9						99.97%
Z-FA-FMK		Caspase-2	Caspase-3			Caspase-6	Caspase-7								99.14%
Z-VDVAD-FMK		Caspase-2													≥98.0%
AVN-944			Caspase 3					Caspase 8	Caspase 9						99.77%
Paris saponin VII			Caspase-3						Caspase-9						99.96%
L67	Caspase-1														≥98.0%
Peiminine			Caspase 3					Caspase-8	Caspase-9						99.94%
Azadirachtin			Caspase 3												99.06%
Almorexant			Caspase-3												99.71%
Zerumbone			Caspase 3												99.87%
Deltamethrin			Caspase 3												99.93%
Triclabendazole			Caspase 3					Caspase-8	Caspase-9						98.72%
(R)-Sulforaphane			Procaspase-3												99.48%
Ossirene	Caspase-1														≥98.0%
MX1013												Caspase			≥99.0%
Asperosaponin VI			Caspase 3												98.91%
TC11									Caspase-9						98.04%
Cystamine			Caspase 3, IC₅₀: 23.6 μM												99.79%
Cystamine dihydrochloride			Caspase 3, IC₅₀: 23.6 μM												≥98.0%
Z-LEVD-FMK				Caspase-4											≥98.0%
Thiabendazole			Caspase 3						Caspase-9						99.77%
Ac-YVAD-CHO	Caspase-1														98.97%
Z-WEHD-FMK	Caspase-1														≥98.0%
δ-Secretase inhibitor 11			Caspase-3, IC₅₀: 31.86 ± 1. μM					Caspase-8, IC₅₀: 86.71 ± 10 μM							99.06%
N-Acetyl-L-tryptophan	Caspase-1														99.38%
Pralnacasan	Interleukin-1β converting enzyme, Ki: 1.4 nM														99.83%
Caspase-9 Inhibitor III									Caspase-9						99.52%
Ac-WEHD-AFC TFA	Caspase-1														99.01%
2-HBA			Caspase-3							Caspase-10					99.09%
5,7,4'-Trimethoxyflavone			Caspase-3												99.65%
Trifloxystrobin			Caspase 3					Caspase-8	Caspase-9						99.49%
Chelidonic acid	Caspase-1														99.91%
Ac-YVAD-pNA	Caspase-1														99.96%
Fenbufen	Caspase-1, IC₅₀: 4.4 μM		Caspase-3, IC₅₀: 1.2 μM	Caspase-4, IC₅₀: 0.57 μM	Caspase-5, IC₅₀: 0.87 μM				Caspase-9, IC₅₀: 0.76 μM						99.33%
CZL55	Caspase-1, IC₅₀: 24 nM														98.70%
Boc-Asp(OMe)-fluoromethyl ketone												Caspase			≥98.0%
PETCM			Caspase 3												99.68%
Biotin-VAD-FMK												Caspase			≥98.0%
5,7-Dihydroxychromone			Caspase-3						Caspase-9						99.94%
Almorexant hydrochloride			Caspase-3												99.98%
L6H21			Caspase 3												99.46%
ASP3026			Caspase-3												99.88%
MPT0B392												Caspase			99.63%
Arnicolide D												Caspase			99.20%
AC-VEID-CHO TFA			Caspase 3, IC₅₀: 13.6 nM			Caspase-6, IC₅₀: 16.2 nM	Caspase-7, IC₅₀: 162.1 nM								98.7%
Heptelidic acid			Caspase-3
14-Deoxyandrographolide			Caspase 3												99.47%
MMPSI			human Caspase-3, IC₅₀: 1.7 μM												99.97%
Destruxin B			Caspase-3												99.86%
Aspidin BB			Caspase-3												98.08%
Caspase-3-IN-1	Caspase-1, IC₅₀: >10000 nM		Caspase-3, IC₅₀: 14.5 ± 1.6 nM			Caspase-6, IC₅₀: >5000 nM	Caspase-7, IC₅₀: 21.8 ± 3.5 nM	Caspase-8, IC₅₀: >50000 nM
Sanggenon G			Caspase-3					Caspase-8	Caspase-9
ML132	Caspase-1, IC₅₀: 34.9 nM			Caspase-4, IC₅₀: 1.27 μM	Caspase-5, IC₅₀: 0.85 μM			Caspase-8, IC₅₀: 4.18 μM	Caspase-9, IC₅₀: 2.85 μM						98.75%
Procaspase-3/6 activator 1			Procaspase-3, EC₅₀: 2.4 ± 0.2 μM			Procaspase-6, EC₅₀: 2.8 ± 0.3 μM									98.97%
Mca-YVADAP-Lys(Dnp)-OH TFA	Caspase-1														98.85%
cRIPGBM chloride	Caspase-1														99.73%
M190S			Caspase 3, EC₅₀: 23.4 nM												99.84%
Ivachtin			Caspase-3, IC₅₀: 23 nM												99.71%
Dehydrotrametenolic acid			Caspase-3												99.95%
EP1013												Caspase
Thevetiaflavone			Caspase-3												≥98.0%
TD1092			Caspase 3				Caspase-7								99.49%
p-nitro-Pifithrin-α			Caspase-3
BBR-BODIPY									Caspase-9						98.15%
Ac-Tyr-Val-Lys-Asp-aldehyde	Caspase-1														99.89%
KEA1-97			Caspase 3, IC₅₀: 10 μM												98.05%
Nivalenol												Caspase			≥99.0%
PARP-1-IN-2			Caspase-3						Caspase-9						98.80%
Ginsenoside Rh4			Caspase 3					Caspase 8	Caspase 9						99.28%
Magnesium isoglycyrrhizinate hydrate	Caspase-1														99.51%
CASP8-IN-1								Caspase 8, IC₅₀: 0.7 μM							98.97%
Duocarmycin A			Procaspase-3						Caspase-9
cRIPGBM	Caspase-1
Ac-LDESD-AMC		Caspase-2
Z-LEED-FMK	Caspase-1			Caspase-4										Caspase-13
15-Acetoxyscirpenol												Caspase			99.35%
Akt1/Akt2-IN-2			Caspase-3												98.57%
Ganoderic acid T1			Caspase 3						Caspase-9
Mca-DEVDAP-K(Dnp)-OH			Caspase-3
Cimiside E			Caspase 3
IETD-CHO								Caspase-8
Caspase-3 activator 3			Caspase 3
PAWI-2			Caspase 3				Caspase-7
Ac-WEHD-AFC	Caspase-1
WF-210			Procaspase-3, IC₅₀: 0.95 μM
TRP-601		Caspase-2	Caspase 3
Caspase-3/7 activator 2			Caspase-3				Caspase-7
BRD4 Inhibitor-15			Caspase-3 Procaspase-3
Apoptotic agent-2			Caspase 3
N1,N11-Diethylnorspermine			Caspase 3
Caspase-3/7 activator 1			Caspase-3				Caspase-7
PROTAC BRD4 Degrader-6			Caspase 3
CZL80	Caspase-1, IC₅₀: 0.01 μM
Caspase-3 activator 4			Caspase 3
KDM1/CDK1-IN-1			Caspase-3
Z-LEHD-FMK TFA									Caspase-9
LSD1-IN-26			Caspase-3						Caspase-9
Ac-DMQD-AMC			Caspase 3
Anticancer agent 64			Caspase 3				Caspase-7
Ac-AAVALLPAVLLALLAP-DEVD-CHO			Caspase 3
Akt/mTOR-IN-1			Caspase 3
Ac-AAVALLPAVLLALLAP-LEVD-CHO				Caspase-4
Z-ATAD-FMK									Caspase-9
Bcl-2-IN-6							Caspase-7
Dynorphin A TFA			Caspase-3
C105SR			Caspase 3				Caspase-7
Aviculin							Caspase-7		Caspase-9
14-Deoxyandrographolide (Standard)			Caspase 3
M867			Caspase 3
Bcl-2-IN-7							Caspase-7
Anticancer agent 201			Caspase-3
Astin B			Caspase-3						Caspase-9
EGFR-IN-109			Caspase-3						Caspase-9
CDK1/2/4-IN-1			Caspase 3
VEGFR-2-IN-40			Caspase 3
LM-021	Caspase-1
Apoptotic agent-3			Caspase 3
Anticancer agent 43			Caspase 3												98.58%
Lycopodine			Caspase-3
Ac-LEVD-CHO				Caspase-4
Ginsenoside Rh2 (Standard)								Caspase-8	Caspase-9
PARP1-IN-17			Caspase 3
EM20-25									Caspase 9
Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone			Caspase 3
Mca-YVADAP-Lys(Dnp)-OH	Caspase-1
28-Deoxonimbolide			Caspase-3					Caspase-8	Caspase-9
Apoptosis inducer 19			Caspase 3
Caspase-3/7 activator 3			Caspase-3				Caspase-7
Ac-YVAD-CHO acetate	Caspase-1
Ac-DEVD-CMK			Caspase-3
Anticancer agent 63			Caspase-3
KTt-45			Caspase 3						Caspase-9
Ac-Trp-Glu-His-Asp-Aldehyde	Caspase-1, Ki: 56 pM
Ganoderic acid Mk			Caspase-3						Caspase-9
Ac-AAVALLPAVLLALLAP-YVAD-CHO	Caspase-1
AC-VEID-CHO			Caspase 3, IC₅₀: 13.6 nM			Caspase-6, IC₅₀: 16.2 nM	Caspase-7, IC₅₀: 162.1 nM
Patuletin			Caspase 3
Mofarotene			Caspase 3						Caspase-9
AD-2646			Caspase 3					Caspase-8	Caspase-9
N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride			Caspase-3, IC₅₀: 12.0 μM			Caspase-6, IC₅₀: 54.5 μM	Caspase-7, IC₅₀: 19.3 μM

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