2. GPCR/G Protein
  3. P2Y Receptor
  4. MRS2395

MRS2395, an dipivaloyl derivative, is a potent P2Y12 receptor antagonist. MRS2395 inhibits ADP-induced platelet activation with a Ki of 3.6 μM. MRS2395 inhibits cAMP induced by ADP in rat platelets in the presence of PGE1 with an IC50 of 7 µM. MRS2395 enhances platelet dense granule release in response to TRAP-6.

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MRS2395 Chemical Structure

MRS2395 Chemical Structure

CAS No. : 491611-55-3

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MRS2395 Related Antibodies

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Description

MRS2395, an dipivaloyl derivative, is a potent P2Y12 receptor antagonist. MRS2395 inhibits ADP-induced platelet activation with a Ki of 3.6 μM. MRS2395 inhibits cAMP induced by ADP in rat platelets in the presence of PGE1 with an IC50 of 7 µM. MRS2395 enhances platelet dense granule release in response to TRAP-6[1][2].

Molecular Weight

439.94

Formula

C20H30ClN5O4
CAS No.
SMILES

CNC1=C2N=CN(CC(COC(C(C)(C)C)=O)COC(C(C)(C)C)=O)C2=NC(Cl)=N1
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Purity & Documentation
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MRS2395 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MRS2395491611-55-3MRS 2395MRS-2395P2Y ReceptorDipivaloylP2Y12ADPplatelet activationcAMPPGE1TRAP-6Inhibitorinhibitorinhibit

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