1. Anti-infection
  2. Bacterial
  3. MRV03-070

MRV03-070 is an inhibitor of colibactin-activating peptidase ClbP with an IC50 value of 69 nM, acts like biosynthetic precursor precolibactin.

For research use only. We do not sell to patients.

MRV03-070 Chemical Structure

MRV03-070 Chemical Structure

CAS No. : 2797066-29-4

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Description

MRV03-070 is an inhibitor of colibactin-activating peptidase ClbP with an IC50 value of 69 nM, acts like biosynthetic precursor precolibactin[1].

In Vitro

MRV03-070 (compound 4) (0.01 nM-0.1 mM for 1 h) inhibits ClbP acitivity with IC50s of 69 nM and 27 nM, respectively, measured both in vitro and in E. coli BL21 overexpressing ClbP[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

236.03

Formula

C10H13BN2O4

CAS No.
SMILES

OB([C@@H](CC(N)=O)NC(C1=CC=CC=C1)=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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MRV03-070 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
MRV03-070
Cat. No.:
HY-151631
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