1. Apoptosis
  2. MDM-2/p53
  3. MX69-102

MX69-102 (compound MX69-102) is an MDM-2/p53 inhibitor, inducing MDM2 degradation, resulting in p53 activation and cancer cell apoptosis. MX69-102 shows effective inhibition on xenografted human MDM2-overexpressing ALL in SCID mice..

For research use only. We do not sell to patients.

MX69-102 Chemical Structure

MX69-102 Chemical Structure

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Description

MX69-102 (compound MX69-102) is an MDM-2/p53 inhibitor, inducing MDM2 degradation, resulting in p53 activation and cancer cell apoptosis. MX69-102 shows effective inhibition on xenografted human MDM2-overexpressing ALL in SCID mice.[1].

Molecular Weight

518.62

Formula

C29H30N2O5S

SMILES

O=C(C1=CC=CC(NS(=O)(C2=CC=C(C3=C2)NC([C@H]4[C@@H]3OCC4)C5=CC=C(C=C5)C(C(C)C)=O)=O)=C1)C

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
MX69-102
Cat. No.:
HY-169240
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