2. Cytoskeleton
  3. Myosin
  4. Myosin modulator 1

Myosin modulator 1 (Compound B141) is a modulator for myosin, that inhibits ATPase in rabbits psoas, porcine atria and in porcine ventricle, with IC25s of 0.42, 0.13 and 3.09 μM, respectively. Myosin modulator 1 regulates systolic cardiac performance in Sprague Dawley rats.

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Myosin modulator 1 Chemical Structure

Myosin modulator 1 Chemical Structure

CAS No. : 3034189-56-2

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Description

Myosin modulator 1 (Compound B141) is a modulator for myosin, that inhibits ATPase in rabbits psoas, porcine atria and in porcine ventricle, with IC25s of 0.42, 0.13 and 3.09 μM, respectively. Myosin modulator 1 regulates systolic cardiac performance in Sprague Dawley rats[1].

Molecular Weight

389.33

Formula

C18H14F3N5O2
CAS No.
SMILES

O=C(N(CC(N[C@@H](C1=NC=C(C#N)C=C1F)C)=O)C2)NC3=C2C(F)=C(F)C=C3
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Myosin modulator 1 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Myosin modulator 13034189-56-2Myosin modulator1Myosin modulator-1Myosinhypertrophic cardiomyopathydiastolic dysfunctionSprague Dawley ratsInhibitorinhibitorinhibit

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