N-Acetyl-L-aspartic acid-d₃

Name: N-Acetyl-L-aspartic acid-d 3
Brand: MedChemExpress
SKU: HY-113524S
Rating: 4.5 (1 reviews)

Cat. No.: HY-113524S Purity: 99.77%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

N-Acetyl-L-aspartic acid-d₃ is the deuterium labeled N-Acetyl-L-aspartic acid. N-Acetyl-L-aspartic acid is a derivative of aspartic acid.

For research use only. We do not sell to patients.

N-Acetyl-L-aspartic acid-d<sub>3</sub> Chemical Structure

N-Acetyl-L-aspartic acid-d₃ Chemical Structure

CAS No. : 284665-15-2

Size	Price	Stock	Quantity
1 mg	USD 180	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of N-Acetyl-L-aspartic acid-d₃:

N-Acetyl-L-aspartic acid In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

N-Acetyl-L-aspartic acid-d₃ is the deuterium labeled N-Acetyl-L-aspartic acid. N-Acetyl-L-aspartic acid is a derivative of aspartic acid.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

178.16

Formula

C₆H₆D₃NO₅

CAS No.

284665-15-2

Unlabeled CAS

997-55-7

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C([2H])([2H])C(C(O)=O)([2H])NC(C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 62.5 mg/mL (350.81 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.6129 mL	28.0647 mL	56.1293 mL
5 mM	1.1226 mL	5.6129 mL	11.2259 mL
10 mM	0.5613 mL	2.8065 mL	5.6129 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.77%

Select Batch:

Data Sheet (274 KB) SDS (251 KB)

COA (252 KB) HNMR (158 KB) RP-HPLC (339 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Birken DL, et al. N-acetyl-L-aspartic acid: a literature review of a compound prominent in 1H-NMR spectroscopic studies of brain. Neurosci Biobehav Rev. 1989 Spring;13(1):23-31. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	5.6129 mL	28.0647 mL	56.1293 mL	140.3233 mL
	5 mM	1.1226 mL	5.6129 mL	11.2259 mL	28.0647 mL
	10 mM	0.5613 mL	2.8065 mL	5.6129 mL	14.0323 mL
	15 mM	0.3742 mL	1.8710 mL	3.7420 mL	9.3549 mL
	20 mM	0.2806 mL	1.4032 mL	2.8065 mL	7.0162 mL
	25 mM	0.2245 mL	1.1226 mL	2.2452 mL	5.6129 mL
	30 mM	0.1871 mL	0.9355 mL	1.8710 mL	4.6774 mL
	40 mM	0.1403 mL	0.7016 mL	1.4032 mL	3.5081 mL
	50 mM	0.1123 mL	0.5613 mL	1.1226 mL	2.8065 mL
	60 mM	0.0935 mL	0.4677 mL	0.9355 mL	2.3387 mL
	80 mM	0.0702 mL	0.3508 mL	0.7016 mL	1.7540 mL
	100 mM	0.0561 mL	0.2806 mL	0.5613 mL	1.4032 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.