2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. N-Acetylmannosamine 6-phosphate sodium salt

N-Acetylmannosamine 6-phosphate sodium salt  (Synonyms: ManNAc-6P sodium salt)

Cat. No.: HY-160821A Purity: ≥95.0%
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N-Acetylmannosamine 6-phosphate sodium salt is a metabolic intermediate in the breakdown of sialic acid (Neu5Ac) by Staphylococcus aureus. N-Acetylmannosamine 6-phosphate sodium salt reduces the binding ability of transcriptional regulator NanR to DNA, and thus regulates the metabolic pathway of sialic acid.

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N-Acetylmannosamine 6-phosphate sodium salt Chemical Structure

N-Acetylmannosamine 6-phosphate sodium salt Chemical Structure

CAS No. : 335275-62-2

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Based on 1 publication(s) in Google Scholar

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Description

N-Acetylmannosamine 6-phosphate sodium salt is a metabolic intermediate in the breakdown of sialic acid (Neu5Ac) by Staphylococcus aureus. N-Acetylmannosamine 6-phosphate sodium salt reduces the binding ability of transcriptional regulator NanR to DNA, and thus regulates the metabolic pathway of sialic acid[1].

Molecular Weight

323.17

Formula

C8H15NNaO9P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=P(O)(O[Na])OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](C=O)NC(C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 125 mg/mL (386.79 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0943 mL 15.4717 mL 30.9435 mL
5 mM 0.6189 mL 3.0943 mL 6.1887 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥95.0%

SDS (251 KB)

COA (249 KB) HNMR (274 KB) CNMR (264 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.0943 mL 15.4717 mL 30.9435 mL 77.3587 mL
5 mM 0.6189 mL 3.0943 mL 6.1887 mL 15.4717 mL
10 mM 0.3094 mL 1.5472 mL 3.0943 mL 7.7359 mL
15 mM 0.2063 mL 1.0314 mL 2.0629 mL 5.1572 mL
20 mM 0.1547 mL 0.7736 mL 1.5472 mL 3.8679 mL
25 mM 0.1238 mL 0.6189 mL 1.2377 mL 3.0943 mL
30 mM 0.1031 mL 0.5157 mL 1.0314 mL 2.5786 mL
40 mM 0.0774 mL 0.3868 mL 0.7736 mL 1.9340 mL
50 mM 0.0619 mL 0.3094 mL 0.6189 mL 1.5472 mL
60 mM 0.0516 mL 0.2579 mL 0.5157 mL 1.2893 mL
80 mM 0.0387 mL 0.1934 mL 0.3868 mL 0.9670 mL
100 mM 0.0309 mL 0.1547 mL 0.3094 mL 0.7736 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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N-Acetylmannosamine 6-phosphate sodium salt Related Classifications

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Keywords:

N-Acetylmannosamine 6-phosphate335275-62-2ManNAc-6PEndogenous MetaboliteStaphylococcus aureussialic acidNeu5AcInhibitorinhibitorinhibit

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