2. PROTAC
  3. PROTAC Linkers
  4. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester

N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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N-(Azido-PEG4)-N-Boc-PEG4-NHS ester Chemical Structure

N-(Azido-PEG4)-N-Boc-PEG4-NHS ester Chemical Structure

CAS No. : 2112731-96-9

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N-(Azido-PEG4)-N-Boc-PEG4-NHS ester Related Antibodies

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Description

N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs[1] N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC50 & Target

PEGs

 

Molecular Weight

663.71

Formula

C28H49N5O13
CAS No.
Appearance

Liquid

Color

Colorless to off-white

SMILES

O=C(OC(C)(C)C)N(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Purity: ≥97.0%

COA (241 KB) HNMR (117 KB) MS (107 KB)

Handling Instructions (2659 KB)
References
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N-(Azido-PEG4)-N-Boc-PEG4-NHS ester Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-(Azido-PEG4)-N-Boc-PEG4-NHS ester2112731-96-9PROTAC LinkersPROTAClinkerPEGAzidoInhibitorinhibitorinhibit

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