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  4. N-Methyl-DL-valine hydrochloride

N-Methyl-DL-valine hydrochloride  (Synonyms: N-Methylvaline hydrochloride)

Cat. No.: HY-W142140A Purity: ≥98.0%
COA Handling Instructions

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N-Methyl-DL-valine (N-Methylvaline) hydrochloride is a valine derivant, is metabolized to cysteine, alanine, tyrosine, tryptophan, citric acid, and succinic acid in the sprout. N-Methyl-DL-valine hydrochloride involves in the modification of monomethyl auristatin F (MMAF), an anti-tubulin agent, makes it hydrophobic functionalization and increases cell permeability.

For research use only. We do not sell to patients.

N-Methyl-DL-valine hydrochloride Chemical Structure

N-Methyl-DL-valine hydrochloride Chemical Structure

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100 mg USD 70 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of N-Methyl-DL-valine hydrochloride:

N-Methyl-DL-valine hydrochloride Related Antibodies

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Description

N-Methyl-DL-valine (N-Methylvaline) hydrochloride is a valine derivant, is metabolized to cysteine, alanine, tyrosine, tryptophan, citric acid, and succinic acid in the sprout. N-Methyl-DL-valine hydrochloride involves in the modification of monomethyl auristatin F (MMAF), an anti-tubulin agent, makes it hydrophobic functionalization and increases cell permeability[1][2].

Molecular Weight

167.63

Formula

C6H14ClNO2
Appearance

Solid-Liquid Mixture

Color

White to off-white

SMILES

O=C(C(C(C)C)NC)O.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (745.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.9655 mL 29.8276 mL 59.6552 mL
5 mM 1.1931 mL 5.9655 mL 11.9310 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.9655 mL 29.8276 mL 59.6552 mL 149.1380 mL
5 mM 1.1931 mL 5.9655 mL 11.9310 mL 29.8276 mL
10 mM 0.5966 mL 2.9828 mL 5.9655 mL 14.9138 mL
15 mM 0.3977 mL 1.9885 mL 3.9770 mL 9.9425 mL
20 mM 0.2983 mL 1.4914 mL 2.9828 mL 7.4569 mL
25 mM 0.2386 mL 1.1931 mL 2.3862 mL 5.9655 mL
30 mM 0.1989 mL 0.9943 mL 1.9885 mL 4.9713 mL
40 mM 0.1491 mL 0.7457 mL 1.4914 mL 3.7284 mL
50 mM 0.1193 mL 0.5966 mL 1.1931 mL 2.9828 mL
60 mM 0.0994 mL 0.4971 mL 0.9943 mL 2.4856 mL
80 mM 0.0746 mL 0.3728 mL 0.7457 mL 1.8642 mL
100 mM 0.0597 mL 0.2983 mL 0.5966 mL 1.4914 mL
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N-Methyl-DL-valine hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Methyl-DL-valineN-MethylvalineOthersInhibitorinhibitorinhibit

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