2. Apoptosis
  3. Apoptosis
  4. n-Octyl caffeate

n-Octyl caffeate shows anti-cancer and apoptosis inducing activity in highly liver-metastatic murine colon 26-L5 carcinoma cell lines.

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n-Octyl caffeate Chemical Structure

n-Octyl caffeate Chemical Structure

CAS No. : 478392-41-5

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n-Octyl caffeate Related Antibodies

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Description

n-Octyl caffeate shows anti-cancer and apoptosis inducing activity in highly liver-metastatic murine colon 26-L5 carcinoma cell lines[1].

Cellular Effect
Cell Line Type Value Description References
BeWo IC50
13.12 μM
Compound: I-13
Antitumor activity against human Bewo cells assessed as inhibition of cell growth by MTT assay
Antitumor activity against human Bewo cells assessed as inhibition of cell growth by MTT assay
[PMID: 25160837]
HeLa IC50
34.94 μM
Compound: I-13
Antitumor activity against human HeLa cells assessed as inhibition of cell growth by MTT assay
Antitumor activity against human HeLa cells assessed as inhibition of cell growth by MTT assay
[PMID: 25160837]
HepG2 IC50
54.29 μM
Compound: I-13
Antitumor activity against human HepG2 cells assessed as inhibition of cell growth by MTT assay
Antitumor activity against human HepG2 cells assessed as inhibition of cell growth by MTT assay
[PMID: 25160837]
HL-60 IC50
8.29 μM
Compound: I-13
Antitumor activity against human HL60 cells assessed as inhibition of cell growth by MTT assay
Antitumor activity against human HL60 cells assessed as inhibition of cell growth by MTT assay
[PMID: 25160837]
RAW264.7 EC50
0.06 μM
Compound: 8, n-octyl caffeate
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells assessed as nitrite accumulation administered 1 hr before LPS challenge and measured after 24 hrs by Griess reagent assay
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells assessed as nitrite accumulation administered 1 hr before LPS challenge and measured after 24 hrs by Griess reagent assay
[PMID: 18667320]
RAW264.7 EC50
1.588 μM
Compound: 8, n-octyl caffeate
Cytotoxicity against mouse RAW264.7 cells assessed as cell survival after 24 hrs by MTT assay
Cytotoxicity against mouse RAW264.7 cells assessed as cell survival after 24 hrs by MTT assay
[PMID: 18667320]
SGC-7901 IC50
55.96 μM
Compound: I-13
Antitumor activity against human SGC7901 cells assessed as inhibition of cell growth by MTT assay
Antitumor activity against human SGC7901 cells assessed as inhibition of cell growth by MTT assay
[PMID: 25160837]
SiHa IC50
45.93 μM
Compound: I-13
Antitumor activity against human SiHa cells assessed as inhibition of cell growth by MTT assay
Antitumor activity against human SiHa cells assessed as inhibition of cell growth by MTT assay
[PMID: 25160837]
Molecular Weight

292.37

Formula

C17H24O4
CAS No.
SMILES

O=C(OCCCCCCCC)/C=C/C1=CC=C(O)C(O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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n-Octyl caffeate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

n-Octyl caffeate478392-41-5ApoptosisInhibitorinhibitorinhibit

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