2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Nav1.3 channel inhibitor 1

Nav1.3 channel inhibitor 1 (compound 15b) is a state-dependent voltage-gated sodium channel Nav1.3 inhibitor (IC50=20 nM). Nav1.3 channel inhibitor 1 can penetrate the blood-brain barrier and can be used in the research of nervous system diseases.

For research use only. We do not sell to patients.

Nav1.3 channel inhibitor 1 Chemical Structure

Nav1.3 channel inhibitor 1 Chemical Structure

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Nav1.3 channel inhibitor 1 Related Antibodies

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Description

Nav1.3 channel inhibitor 1 (compound 15b) is a state-dependent voltage-gated sodium channel Nav1.3 inhibitor (IC50=20 nM). Nav1.3 channel inhibitor 1 can penetrate the blood-brain barrier and can be used in the research of nervous system diseases[1].

IC50 & Target

IC50: 20 nM (Nav1.3)[1].
Molecular Weight

435.47

Formula

C19H15F2N3O3S2
SMILES

O=C(C1C(C2=CC=C(F)C(F)=C2)C1)NC3=CC=C(S(=O)(NC4=NC=CS4)=O)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Nav1.3 channel inhibitor 1 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nav1.3 channel inhibitor 1Sodium ChannelNa channelsNa+ channelsHepG2CNSnervous system diseasesInhibitorinhibitorinhibit

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Nav1.3 channel inhibitor 1
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HY-155058
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