2. Metabolic Enzyme/Protease
  3. Cathepsin
  4. NC 2300

NC 2300 (VEL-0230)is a selective and orally active cysteine cathepsin inhibitor with the IC50 values of 284, 34.5, and 186 nM for cathepsin B, K, and S, respectively.NC 2300 can be used for study of diseases involving bone mineral disorders.

For research use only. We do not sell to patients.

NC 2300 Chemical Structure

NC 2300 Chemical Structure

CAS No. : 221144-20-3

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NC 2300 Related Antibodies

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Cathepsin B Cathepsin C Cathepsin D Cathepsin E Cathepsin K Cathepsin L Cathepsin S

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Description

NC 2300 (VEL-0230)is a selective and orally active cysteine cathepsin inhibitor with the IC50 values of 284, 34.5, and 186 nM for cathepsin B, K, and S, respectively.NC 2300 can be used for study of diseases involving bone mineral disorders[1][2].

Molecular Weight

309.33

Formula

C14H24NNaO5
CAS No.
SMILES

CC(C)COC[C@H](CC(C)C)NC([C@@H]1[C@H](O1)C(O[Na])=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NC 2300 Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NC 2300221144-20-3VEL 0230NC2300NC-2300VEL0230VEL-0230Cathepsinmultiple myelomaosteoporosisbone metastasesrheumatoid arthritisInhibitorinhibitorinhibit

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