Cathepsin Inhibitors

Cathepsin B

Cathepsin C

Cathepsin D

Cathepsin E

Cathepsin K

Cathepsin L

Cathepsin S

Cathepsin Inducers, Inhibitors, Antagonists & Activators

Product Name	Cathepsin B	Cathepsin C	Cathepsin D	Cathepsin E	Cathepsin K	Cathepsin L	Cathepsin S	Purity
Cathepsin Inhibitor 4							cathepsin S, Ki: 0.04 nM
E-64					cathepsin K	cathepsin L		99.96%
CA-074 methyl ester	Cathepsin B							99.62%
Calpeptin					cathepsin K			≥98.0%
CA-074	Cathepsin B							99.88%
L-Homocysteine						cathepsin L		≥98.0%
LY 3000328							cathepsin S	98.00%
Z-FY-CHO						cathepsin L
Odanacatib					cathepsin K			99.82%
SID 26681509						cathepsin L		98.70%
Z-FA-FMK	Cathepsin B					cathepsin L		99.14%
Balicatib	Cathepsin B, IC₅₀: 61 nM				cathepsin K, IC₅₀: 22 nM	cathepsin L, IC₅₀: 48 nM	cathepsin S, IC₅₀: 2900 nM	98.00%
Cathepsin L-IN-2	Cathepsin B					cathepsin L		98.27%
Hepcidin-1 (mouse) (TFA)					cathepsin K			98.94%
Z-WEHD-FMK	Cathepsin B							≥98.0%
LHVS	Cathepsin B				cathepsin K	cathepsin L	cathepsin S	98.03%
Petesicatib							cathepsin S	99.66%
RO5461111							human Cathepsin S, IC₅₀: 0.4 nM murine Cathepsin S, IC₅₀: 0.5 nM	98.17%
GSK-2793660		Cathepsin C						99.91%
Relacatib					cathepsin K	cathepsin L		99.99%
L-006235	Cathepsin B				cathepsin K			99.96%
VBY-825					cathepsin K		cathepsin S	99.81%
3-Epiursolic Acid						cathepsin L, IC₅₀: 6.5 μM		99.77%
Aurantiamide acetate						cathepsin L		99.60%
ONO-5334					cathepsin K			99.83%
Gü2602					cathepsin K			98.13%
2-Cyanopyrimidine					cathepsin K			99.92%
Z-Phe-Tyr(tBu)-diazomethylketone						cathepsin L		≥99.0%
Cathepsin K inhibitor 6	Cathepsin B, IC₅₀: 0.3 μM				cathepsin K, IC₅₀: 17 nM	cathepsin L, IC₅₀: 0.05 μM		98.18%
E 64c		Cathepsin C						99.73%
Hepcidin-1 (mouse)					cathepsin K
MIV-247							cathepsin S
Cathepsin D and E FRET Substrate			Cathepsin D	Cathepsin E
Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2			Cathepsin D
FGA146						cathepsin L, Ki: 0.87 μM
Ac-Leu-Val-Lys-Aldehyde	Cathepsin B, IC₅₀: 4 nM
Cathepsin C-IN-4		Cathepsin C
JNJ 10329670							cathepsin S, Ki: 34 nM
Cathepsin K inhibitor 3					cathepsin K, IC₅₀: 0.5 nM
Z-Arg-Arg-4MβNA triacetate	Cathepsin B
Cathepsin L/S-IN-1						cathepsin L, IC₅₀: 4.10 μM	cathepsin S, IC₅₀: 1.79 μM
ABP 25					cathepsin K
Cathepsin L-IN-4						cathepsin L
TS-24							cathepsin S, IC₅₀: 4.3 μM	98.96%
Ac-VLPE-FMK	Cathepsin B					cathepsin L		≥99.0%
Tasiamide B			Cathepsin D
SPR38	Cathepsin B, IC₅₀: 11.1 ± 1.2 μM					cathepsin L, IC₅₀: 1.92 ± 0.1 μM
Cathepsin C-IN-3		Cathepsin C
ASPER-29						cathepsin L, IC₅₀: 6.03 μM	cathepsin S, IC₅₀: 5.02 μM
CAA-0225						cathepsin L
Mpro/Cathepsin L-IN-1						cathepsin L
Z-Phe-Phe-Diazomethylketone						cathepsin L
SmCB1-IN-1	S. mansoni cathepsin B1, IC₅₀: 0.05 μM
FGA145	Cathepsin B, Ki: 206 nM					cathepsin L, Ki: 53 nM
AM4299B	Cathepsin B, IC₅₀: 0.7 μM					cathepsin L, IC₅₀: 0.5 μM
S2160	Cathepsin B
SQ 32602				Cathepsin E, IC₅₀: 88 nM
Cathepsin L-IN-5						cathepsin L, IC₅₀: 0.27 nM
TB-11			Cathepsin D, IC₅₀: 0.126 nM	Cathepsin E, IC₅₀: 1.92 nM
SARS-CoV-2-IN-77						cathepsin L, Ki: 111 nM	cathepsin S, Ki: 103 nM

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