2. Protein Tyrosine Kinase/RTK
  3. Pyk2
  4. NCGC00188636

NCGC00188636 is a novel covalent pyruvate kinase (PYK) inhibitor. NCGC00188636 blocks nucleotide binding to the active site of pyruvate kinase. NCGC00188636 can be used for the research of the metabolism of many organisms and cell types.

For research use only. We do not sell to patients.

NCGC00188636 Chemical Structure

NCGC00188636 Chemical Structure

CAS No. : 1039980-33-0

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Based on 1 publication(s) in Google Scholar

NCGC00188636 Related Antibodies

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Description

NCGC00188636 is a novel covalent pyruvate kinase (PYK) inhibitor. NCGC00188636 blocks nucleotide binding to the active site of pyruvate kinase. NCGC00188636 can be used for the research of the metabolism of many organisms and cell types.

In Vitro

NCGC00188636 (DBS) (50 μM) has inhibition activity for LmPYK in time-dependent manner[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

NCGC00188636 Related Antibodies
Molecular Weight

319.36

Formula

C14H9NO4S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C1=CC=CC=C1SC(C2=C3C=CC=C2)=NS3(=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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NCGC00188636 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NCGC001886361039980-33-0NCGC 00188636NCGC-00188636Pyk2Proline-rich tyrosine kinase 2pyruvate kinase (PYK)nucleotidebindingmetabolismorganismscellInhibitorinhibitorinhibit

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