Neladenoson dalanate hydrochloride (Synonyms: Neladenoson bialanate hydrochloride; BAY-1067197 hydrochloride)

Cat. No.: HY-115494: FAQs
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Neladenoson dalanate (Neladenoson bialanate; BAY-1067197) hydrochloride is a orally active agonist precursor of partial Adenosine A1 Receptor. Neladenoson dalanate hydrochloride has a good pharmacokinetic and safety profile, can be used for the chronic heart diseases.

For research use only. We do not sell to patients.

Neladenoson dalanate hydrochloride Chemical Structure

CAS No. : 1239235-25-6

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Other Forms of Neladenoson dalanate hydrochloride:

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Adenosine A₁ receptor (A₁R) Adenosine A_2A receptor (A_2AR) Adenosine A_2B receptor (A_2BR) Adenosine A₃ receptor (A₃R)

Biological Activity
Purity & Documentation
References
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Description

IC₅₀ & Target^[1]

A1R

Clinical Trial

Molecular Weight

752.73

Formula

C₃₅H₃₅Cl₂N₇O₄S₂

CAS No.

1239235-25-6

SMILES

C[C@@H](C(OCCOC1=CC=C(C2=C(C#N)C(SCC3=CSC(C4=CC=C(Cl)C=C4)=N3)=NC(N5CCCC5)=C2C#N)C=C1)=O)NC([C@H](C)N)=O.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Meibom D, et al. Neladenoson Bialanate Hydrochloride: A Prodrug of a Partial Adenosine A1 Receptor Agonist for the Chronic Treatment of Heart Diseases. ChemMedChem. 2017 May 22;12(10):728-737. [Content Brief]

Neladenoson dalanate hydrochloride Related Classifications

Cardiovascular Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Neladenoson dalanate1239235-25-6Neladenoson bialanateBAY-1067197BAY1067197BAY 1067197Adenosine ReceptorP1 receptorpharmacokineticsafety profilechronic heart diseasesorally activeInhibitorinhibitorinhibit

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