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  4. NF(N-Me)GA(N-Me)IL

NF(N-Me)GA(N-Me)IL  (Synonyms: Amylin (22-27) [NMeG24, NMeI26], human (IAPP))

Cat. No.: HY-P5514
Handling Instructions

NF(N-Me)GA(N-Me)IL is a biological active peptide. (This amino acids 22 to 27 fragment is a modification of the human islet amyloid polypeptide hIAPP (NFGAIL) with N-methylation of the amide bonds at G24 and I26. The introduction of two N-methyl rests in the amyloid-core-containing sequence NFGAIL converts this amyloidogenic and cytotoxic sequence into non-amyloidogenic and non-cytotoxic peptide. The peptide is able to bind with high-affinity full-length hIAPP and to inhibit its fibrillogenesis.)

For research use only. We do not sell to patients.

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NF(N-Me)GA(N-Me)IL Chemical Structure

NF(N-Me)GA(N-Me)IL Chemical Structure

CAS No. : 409085-42-3

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Description

NF(N-Me)GA(N-Me)IL is a biological active peptide. (This amino acids 22 to 27 fragment is a modification of the human islet amyloid polypeptide hIAPP (NFGAIL) with N-methylation of the amide bonds at G24 and I26. The introduction of two N-methyl rests in the amyloid-core-containing sequence NFGAIL converts this amyloidogenic and cytotoxic sequence into non-amyloidogenic and non-cytotoxic peptide. The peptide is able to bind with high-affinity full-length hIAPP and to inhibit its fibrillogenesis.)

Molecular Weight

661.79

Formula

C32H51N7O8

CAS No.
Sequence

Asn-Phe-{Sar}-Ala-{Ile(N-Me)}-Leu

Sequence Shortening

NF-{Sar}-A-{Ile(N-Me)}-L

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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NF(N-Me)GA(N-Me)IL Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NF(N-Me)GA(N-Me)IL
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HY-P5514
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