2. GPCR/G Protein
  3. P2Y Receptor
  4. NF340

NF340 is a potent and selective P2Y11 receptor antagonist. NF340 inhibits the activity of P2Y11R by completely combining with ATP-binding amino acid residues. NF340 ameliorates inflammation in human fibroblast-like synoviocytes and can be used for rheumatoid arthritis research.

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NF340 Chemical Structure

NF340 Chemical Structure

CAS No. : 202982-98-7

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NF340 Related Antibodies

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Description

NF340 is a potent and selective P2Y11 receptor antagonist. NF340 inhibits the activity of P2Y11R by completely combining with ATP-binding amino acid residues. NF340 ameliorates inflammation in human fibroblast-like synoviocytes and can be used for rheumatoid arthritis research[1].

IC50 & Target

P2Y11 receptor[1]
Molecular Weight

986.84

Formula

C37H26N4Na4O15S4
CAS No.
SMILES

O=C(NC1=CC(C(NC2=C3C=C(S(=O)(O[Na])=O)C=CC3=CC(S(=O)(O[Na])=O)=C2)=O)=CC=C1C)NC4=CC(C(NC5=C6C=C(S(=O)(O[Na])=O)C=CC6=CC(S(=O)(O[Na])=O)=C5)=O)=CC=C4C
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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NF340 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NF340202982-98-7NF 340NF-340P2Y Receptorselectiveinflammationfibroblast-like synoviocyterheumatoid arthritisInhibitorinhibitorinhibit

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