2. Stem Cell/Wnt
  3. β-catenin
  4. NF764

NF764 is a potent β-catenin (CTNNB1) degrader. NF764 reduces CTNNB1 protein levels in a proteasome-dependent manner. NF764 can be used in the study of cancer.

For research use only. We do not sell to patients.

NF764 Chemical Structure

NF764 Chemical Structure

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Based on 1 publication(s) in Google Scholar

NF764 Related Antibodies

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Description

NF764 is a potent β-catenin (CTNNB1) degrader. NF764 reduces CTNNB1 protein levels in a proteasome-dependent manner. NF764 can be used in the study of cancer[1].

In Vitro

NF764 (1-50 μM; 24 h) decreases CTNNB1 protein levels in a proteasoma-dependent manner in HiBiT-CTNNB1 HEK293 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

NF764 Related Antibodies
Molecular Weight

403.39

Formula

C22H20F3NO3
Appearance

Solid

Color

White to off-white

SMILES

FC(F)(F)C1=C(C2N(C(/C=C/C(C3=CC=CC=C3)=O)=O)CCC2)C=C(OC)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation
References
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NF764 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NF764NF 764NF-764β-cateninBeta cateninHiBiT-CTNNB1 HEK293 cellsInhibitorinhibitorinhibit

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