2. Immunology/Inflammation
  3. COX
  4. Nimesulide-d5

Nimesulide-d5 is a deuterium labeled Nimesulide. Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties[1][2].

For research use only. We do not sell to patients.

Nimesulide-d<sub>5</sub> Chemical Structure

Nimesulide-d5 Chemical Structure

CAS No. : 1330180-22-7

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Based on 1 publication(s) in Google Scholar

Other Forms of Nimesulide-d5:

Nimesulide-d5 Related Antibodies

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Description

Nimesulide-d5 is a deuterium labeled Nimesulide. Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties[1][2].

IC50 & Target[1]

COX-2

0.07-70 μM (IC50)

Molecular Weight

313.34

Formula

C13H7D5N2O5S
CAS No.
Unlabeled CAS

51803-78-2
SMILES

CS(=O)(NC1=CC=C([N+]([O-])=O)C=C1OC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Nimesulide-d5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nimesulide-d51330180-22-7COXCyclooxygenaseDeuteriumlabeledCOX-2anti-inflammatoryanalgesicantipyreticInhibitorinhibitorinhibit

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