2. Metabolic Enzyme/Protease
  3. Ser/Thr Protease
  4. NK3201

NK3201 is an orally active chymase inhibitor (IC50: 2.5, 1.2, and 28 nM for human, dog and hamster chymase). NK3201 inhibits Bleomycin (HY-17565)-induced pulmonary fibrosis. NK3201 inhibits vascular proliferation in grafted vein.

For research use only. We do not sell to patients.

NK3201 Chemical Structure

NK3201 Chemical Structure

CAS No. : 204460-24-2

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NK3201 Related Antibodies

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Description

NK3201 is an orally active chymase inhibitor (IC50: 2.5, 1.2, and 28 nM for human, dog and hamster chymase). NK3201 inhibits Bleomycin (HY-17565)-induced pulmonary fibrosis. NK3201 inhibits vascular proliferation in grafted vein[1][2].

Molecular Weight

567.59

Formula

C31H29N5O6
CAS No.
SMILES

O=C(NC(CC1=CC=CC=C1)C(C(CCCOC2=NC=CC=C2)=O)=O)CN(C(C3=CC=CC=C3)=NC=C4NC=O)C4=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NK3201 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NK3201204460-24-2NK 3201NK-3201Ser/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteasesvascular proliferationpulmonary fibrosisInhibitorinhibitorinhibit

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HY-12514
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