2. Immunology/Inflammation
  3. NOD-like Receptor (NLR)
  4. NLRP3-IN-56

NLRP3-IN-56 (compound 062) is a NLRP3 inhibitor. NLRP3-IN-56 potently inhibits the level of IL-1β secretion by THP-1 cells with an IC50 of 9.7 nM. NLRP3-IN-56 can be used for the study of NLRP3-mediated symptoms and/or diseases.

For research use only. We do not sell to patients.

NLRP3-IN-56 Chemical Structure

NLRP3-IN-56 Chemical Structure

CAS No. : 3048421-42-4

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NLRP3-IN-56 Related Antibodies

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Description

NLRP3-IN-56 (compound 062) is a NLRP3 inhibitor. NLRP3-IN-56 potently inhibits the level of IL-1β secretion by THP-1 cells with an IC50 of 9.7 nM. NLRP3-IN-56 can be used for the study of NLRP3-mediated symptoms and/or diseases[1].

Molecular Weight

383.83

Formula

C20H18ClN3O3
CAS No.
SMILES

OC1=CC(Cl)=CC=C1C(N=N2)=C3C(C=C(C#CC)C=C3)=C2NC[C@H](O)CO
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NLRP3-IN-56 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NLRP3-IN-563048421-42-4NOD-like Receptor (NLR)NLRP3 inhibitorIL-1β secretionNLRP3-mediated symptomsInhibitorinhibitorinhibit

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