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  6. NLS (PKKKRKV)

NLS (PKKKRKV) is a nuclear localization signal (NLS) derived from the simian virus 40 large tumor antigen (SV40 large T antigen), that mediates binding of the karyophilic protein to importin α. NLS (PKKKRKV) can function as a method to enhance nuclear entry in the field of gene transfer research.

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NLS (PKKKRKV) Chemical Structure

NLS (PKKKRKV) Chemical Structure

CAS No. : 95088-49-6

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Description

NLS (PKKKRKV) is a nuclear localization signal (NLS) derived from the simian virus 40 large tumor antigen (SV40 large T antigen), that mediates binding of the karyophilic protein to importin α. NLS (PKKKRKV) can function as a method to enhance nuclear entry in the field of gene transfer research[1][2].

Molecular Weight

883.14

Formula

C40H78N14O8
CAS No.
Sequence Shortening

PKKKRKV
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Purity & Documentation
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NLS (PKKKRKV) Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NLS (PKKKRKV)95088-49-6OthersNLSvirusantigenkaryophilic proteinimportin αgene transferInhibitorinhibitorinhibit

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