2. Peptides
  3. Peptide and Derivatives
  4. Peptides for Drug Delivery
  5. Cell-penetrating Peptides

Cell-penetrating Peptides

Custom Peptide Synthesis

Cell-penetrating Peptides (118):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P4108
    TAT-HA2 Fusion Peptide 923954-79-4 99.69%
    TAT-HA2 Fusion Peptide is a peptide-based delivery agent that combines the pH-sensitive HA2 fusion peptide from Influenza and the cell-penetrating peptide TAT from HIV. TAT-HA2 Fusion Peptide is a transactivator of transcription and hemaglutanin for endosomal release. TAT-HA2 Fusion Peptide enhances cellular uptake of macromolecules.
    TAT-HA2 Fusion Peptide
  • HY-P1848
    Pep-1 (uncapped) 395069-86-0 99.27%
    Pep-1 (uncapped) is a cell-penetrating peptide.
    Pep-1 (uncapped)
  • HY-P5307
    Peptide A5K 99.08%
    Peptide A5K (INF7-A5K-TAT) is an RNP delivery peptide that delivers CRISPR RNPs to T cells. Peptide A5K effectively edits T cells without substantial impact on T cell viability.
    Peptide A5K
  • HY-P2529
    Penetratin 940866-75-1 99.95%
    Penetratin is a peptide derived from the amphiphilic Drosophila Antennapedia homeodomain.
    Penetratin
  • HY-P0281A
    TAT TFA 98.40%
    TAT TFA (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields and the solubility of heterologous proteins.
    TAT TFA
  • HY-P10644A
    CPP9 TFA 99.42%
    CPP9 TFA is a small, amphipathic, cyclic cell penetrating peptide (CPP). CPPs bind directly to the plasma membrane phospholipids and enter mammalian cells via endocytosis, followed by efficient release from the endosome. CPP9 TFA can be used for intracellular delivery of therapeutic agents and chemical probes.
    CPP9 TFA
  • HY-P2483
    Octaarginine 148796-86-5
    Octaarginine is a cell-penetrating peptide (CPP). CPPs show membrane translocation activities. CPPs are used for intracellular delivery of various membrane-impermeable bioactive agents because of their intrinsic ability to gain access to cell interiors. CPPs have also been used to deliver antibacterial agents to target intracellular bacteria.
    Octaarginine
  • HY-P10649
    CPP12
    CPP12 is a small, amphipathic, cyclic cell penetrating peptide (CPP). CPPs bind directly to the plasma membrane phospholipids and enter mammalian cells via endocytosis, followed by efficient release from the endosome. CPP12 can be used for intracellular delivery of therapeutic agents and chemical probes.
    CPP12
  • HY-P1876B
    NLS (PKKKRKV) hydrochloride 99.60%
    NLS (PKKKRKV) hydrochloride is the hydrochloride form of NLS (PKKKRKV) (HY-P1876). NLS (PKKKRKV) is a nuclear localization signal (NLS) derived from the simian virus 40 large tumor antigen (SV40 large T antigen), that mediates binding of the karyophilic protein to importin α. NLS (PKKKRKV) can function as a method to enhance nuclear entry in the field of gene transfer research.
    NLS (PKKKRKV) hydrochloride
  • HY-P0282A
    TAT peptide TFA 99.65%
    TAT peptide (TFA) is a cell penetrating peptide (GRKKRRQRRRPQ) derived from the trans-activating transcriptional activator (Tat) from HIV-1.
    TAT peptide TFA
  • HY-P0311A
    LAH4 TFA 99.17%
    LAH4 TFA, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 TFA possesses high plasmid DNA delivery capacities. LAH4 TFA has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes.
    LAH4 TFA
  • HY-P1575
    TAT (48-57) 253141-50-3 98.65%
    TAT (48-57) is a cell-permeable peptide, derived from HIV-1 transactivator of transcription (Tat) protein residue 48-57.
    TAT (48-57)
  • HY-P1491
    HIV-1 TAT (48-60) 220408-24-2 99.80%
    HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way.
    HIV-1 TAT (48-60)
  • HY-P0133B
    (Arg)9 acetate 99.89%
    (Arg)9 (Nona-L-arginine) acetate is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 acetate has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model.
    (Arg)9 acetate
  • HY-P5284
    RALA peptide 1613231-49-4 99.69%
    RALA peptide is a cell-penetrating peptide. RALA peptide can be as non-viral gene delivery vectors.
    RALA peptide
  • HY-P10068
    LAH5 476169-12-7 99.85%
    LAH5 is an amphipathic cell-penetrating peptide. LAH5 effectively delivers CRISPR-Cas9 components into the nuclei of target cells by forming nanocomplexes with both RNP and RNP/HDR cargo.
    LAH5
  • HY-P2193
    TAT-amide 697226-52-1 99.16%
    TAT-amide is a cell penetrating peptide. Cell-penetrating peptides (CPPs) are short amino acid sequences able to enter different cells.
    TAT-amide
  • HY-P3432
    DfTat 2035480-78-3 98.06%
    DfTat is a dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection.
    DfTat
  • HY-P1351
    Angiopep-2-Cys 906480-09-9 99.94%
    Angiopep-2-cys is a conjugate of Angiopep-2 hydrochloride (HY-P2341) and cysteine. Angiopep-2 hydrochloride is a brain peptide vector. The conjugation of anticancer agents with the Angiopep-2 peptide vector could increase their efficacy in the treatment of brain cancer.
    Angiopep-2-Cys
  • HY-P0307A
    Antennapedia Peptide TFA 98.43%
    Antennapedia Peptide (Penetratin peptide) TFA is a 16 amino acid peptide, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia and is a member of the family of cell-penetrating peptides.
    Antennapedia Peptide TFA