Norharmine

Cat. No.: HY-W067583: FAQs
Data Sheet Handling Instructions Technical Support

Norharmine is a Harmine analogue and an alkaloid. Norharmine is the inhibitors of MAO-A and DYRK1A. Norharmine has weak inhibitory activity against MAO-A and certain inhibitory activity against DYRK1A.

For research use only. We do not sell to patients.

Norharmine Chemical Structure

CAS No. : 6253-19-6

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•Related Small Molecules:

•Related Proteins:

View All Monoamine Oxidase Isoform Specific Products:

View All Isoforms

MAO-A MAO-B

View All DYRK Isoform Specific Products:

View All Isoforms

DYRK1 DYRK2 DYRK3 DYRK4

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target^[1]

MAO-A

DYRK1A

Molecular Weight

198.22

Formula

C₁₂H₁₀N₂O

CAS No.

6253-19-6

SMILES

COC1=CC(NC2=C3C=CN=C2)=C3C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Wurzlbauer A, et al. How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition-The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine. Molecules. 2020 Dec 16;25(24):5962. [Content Brief]

Norharmine Related Classifications

Others

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Norharmine6253-19-6Monoamine OxidaseDYRKMAODual specificity tyrosine phosphorylation regulated kinaseDual specificity tyrosine regulated kinaseharmineInhibitorinhibitorinhibit

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