2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species
  4. NPD926

NPD926 is a small molecule that targets glutathione and induces cancer cell death. The Xc- system and glutathione are therapeutic targets in cancer. NPD926 causes cellular glutathione depletion and subsequent generation of reactive oxygen species (ROS), thereby sensitizing fibroblasts to Xc- system inhibitors. NPD926 is a ROS inducer with anticancer activity..

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NPD926 Chemical Structure

NPD926 Chemical Structure

CAS No. : 384361-79-9

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NPD926 Related Antibodies

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Description

NPD926 is a small molecule that targets glutathione and induces cancer cell death. The Xc- system and glutathione are therapeutic targets in cancer. NPD926 causes cellular glutathione depletion and subsequent generation of reactive oxygen species (ROS), thereby sensitizing fibroblasts to Xc- system inhibitors. NPD926 is a ROS inducer with anticancer activity.[1].

Molecular Weight

479.05

Formula

C29H35ClN2O2
CAS No.
SMILES

CC(OC1=CC=C(C=C1)C(C2=CC=CC=C2)CCN(CC3=CC=C(C=C3)N(C)C)C(CCl)=O)C
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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NPD926 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NPD926384361-79-9NPD 926NPD-926Reactive Oxygen SpeciesInhibitorinhibitorinhibit

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