2. GPCR/G Protein Neuronal Signaling
  3. Neuropeptide Y Receptor
  4. NPY-5 receptor antagonist-1

NPY-5 receptor antagonist-1 (Example 57) is a NPY-5 receptor antagonist (Ki: < 1 μM). NPY-5 receptor antagonist-1 can be used for research of obesity, feeding disorders, as well as other neurological diseases.

For research use only. We do not sell to patients.

NPY-5 receptor antagonist-1 Chemical Structure

NPY-5 receptor antagonist-1 Chemical Structure

CAS No. : 432506-24-6

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5 mg USD 140 In-stock
10 mg USD 220 In-stock
25 mg USD 435 In-stock
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NPY-5 receptor antagonist-1 Related Antibodies

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NPY Y1 receptor NPY Y2 receptor NPY Y4 receptor NPY Y5 receptor

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Description

NPY-5 receptor antagonist-1 (Example 57) is a NPY-5 receptor antagonist (Ki: < 1 μM). NPY-5 receptor antagonist-1 can be used for research of obesity, feeding disorders, as well as other neurological diseases[1].

Molecular Weight

413.51

Formula

C25H27N5O
CAS No.
SMILES

O=C(CN1CCN(CC1)C2=NC=CC=C2)NC3=CC=C4C(C5=C(N4CC)C=CC=C5)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (60.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4183 mL 12.0916 mL 24.1832 mL
5 mM 0.4837 mL 2.4183 mL 4.8366 mL
View the Complete Stock Solution Preparation Table

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4183 mL 12.0916 mL 24.1832 mL 60.4580 mL
5 mM 0.4837 mL 2.4183 mL 4.8366 mL 12.0916 mL
10 mM 0.2418 mL 1.2092 mL 2.4183 mL 6.0458 mL
15 mM 0.1612 mL 0.8061 mL 1.6122 mL 4.0305 mL
20 mM 0.1209 mL 0.6046 mL 1.2092 mL 3.0229 mL
25 mM 0.0967 mL 0.4837 mL 0.9673 mL 2.4183 mL
30 mM 0.0806 mL 0.4031 mL 0.8061 mL 2.0153 mL
40 mM 0.0605 mL 0.3023 mL 0.6046 mL 1.5115 mL
50 mM 0.0484 mL 0.2418 mL 0.4837 mL 1.2092 mL
60 mM 0.0403 mL 0.2015 mL 0.4031 mL 1.0076 mL
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NPY-5 receptor antagonist-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NPY-5 receptor antagonist-1432506-24-6Neuropeptide Y ReceptorNPY receptorInhibitorinhibitorinhibit

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